4′-(4-Methoxy­phen­yl)-1-methyl­chroman-3-spiro-3′-pyrrolidine-2′-spiro-2′′-indan-4,1′′,3′′-trione

In the title compound, C₂₈H₂₃NO₄, the pyrrolidine ring adopts a twist conformation and the pyran ring in the chromanone system adopts a half-chair conformation. The mol­ecules associate via C—H...O inter­actions to form R₂²(18) dimers.

7′-(4-Methoxy­phen­yl)chroman-3-spiro-6′-hexa­hydro-1H-pyrrolo[1,2-c]thia­zole-5′-spiro-3′′-1′′H-indole-4,2′′(3′′H)-dione

In the title compound, C₂₈H₂₄N₂O₄S, the indole ring system is planar, but the pyrrolidine and thia­zole rings adopt an envelope and a twist conformation, respectively. The indole system makes a dihedral angle of 55.7 (1)° with the methoxy­phen­yl ring. The mol­ecular packing in the crystal structure is stabilized by C—H...O and N—H...O hydrogen bonds.

Methyl 2-(1H-indol-3-yl­methyl)-1,2,3,3a,4,11c-hexa­hydro­naphtho­[2′,1′:2,3]­pyrano­[4,5-b]­pyrrole-2-carboxyl­ate

In the title compound, C₂₆H₂₄N₂O₃, the hydrogenated pyrrole ring adopts a twist conformation and the pyran ring adopts a twist–boat conformation. The molecular packing is stabilized by N—H...O and C—H...O intermolecular hydrogen bonds and also by weak intermolecular π–π interactions.

8,12-Dioxa-1,7,10(1,2)-tribenzenacyclo­dodeca­phane-2,5-dien-4-one

In the title compound, C₂₅H₂₀O₃, two of the benzene rings are almost perpendicular to each other, with a dihedral angle of 88.1 (1)°. The mol­ecular packing is stabilized by inter­molecular C—H...O and π–π inter­actions, in addition to van der Waals forces.

2′-Benzo­yl-1′-(4-chloro­phen­yl)-5′,6′,7′,7a′-tetra­hydro­spiro­[indan-2,3′(2′H)-1H-pyrrolizine]-1,3-dione

The title compound, C₂₈H₂₂ClNO₃, has two crystallographically independent mol­ecules in the asymmetric unit. The pyrrolidine ring (A) of the pyrrolizine system adopts an envelope conformation in both mol­ecules, whereas the other five-membered ring (B) adopts an envelope conformation in one mol­ecule and a twist conformation in the other. The mol­ecular packing is stabilized by inter­molecular C—H...O, C—H...π and π–π inter­actions.

Eth­yl 2,2′′-dioxo-2′,3′,5′,6′,7′,7a′-hexa­hydro­acenaphthene-1-spiro-3′-1′H-pyrrolizine-2′spiro-1′′-acenaphthene-1-carboxyl­ate

In the title compound, C₃₂H₂₅NO₄, the mean plane through the pyrrolizidine system is almost perpendicular [dihedral angle 88.9 (1)°] to that through one of the acenaphthene units, and the dihedral angle between the pyrrolizidine and the second acenaphthene system is 81.6 (1)°. In the pyrrolizidine system, one of the rings is in a half-chair conformation while the other is in an envelope conformation. The overall conformation is twisted about the fusion bond. The crystal structure is stabilized by a C—H...O inter­molecular hydrogen bond.

1-(p-Bromo­phen­yl)-5-p-tosyl­perhydro­pyrrolo[3,4-b]pyrrole

In the title compound, C₁₉H₂₁BrN₂O₂S, the fused pyrrolidine rings adopt envelope conformations. The mol­ecular packing is stabilized by weak inter­molecular C—H...O inter­actions and van der Waals forces.

4′-(4-Methoxy­phen­yl)-1′-methyl-9H-fluorene-9-spiro-3′-pyrrolidine-2′-spiro-2′′-indan-1′′,3′′-dione

In the title compound, C₃₂H₂₅NO₃, the pyrrolidine ring and the five-membered ring of the indan moiety adopt twist and envelope conformations, respectively. The mol­ecules in the crystal structure are linked by an inter­molecular C—H...O hydrogen bond, forming chains running along the [01] direction.

3,3-Bis(1H-indol-3-yl)indolin-2-one

In the title compound, C₂₄H₁₇N₃O, the dihedral angles between the planes of the two indole ring systems and the oxindole group are 77.7 (1) and 71.9 (1)°. The mol­ecular packing in the crystal structure is stabilized by an inter­molecular N—H...O hydrogen bond.

2′-(2-Chloro­phen­yl)-1′-nitro-2′,3′,4′,5′,6′,7′-hexa­hydro-1H-indole-3-spiro-3′-1′H-pyrrolizin-2(3H)-one

The structure of the title cyclo­adduct, C₂₀H₁₈N₃O₃Cl, has been determined. The inversion-related mol­ecules are held together by N—H...O hydrogen bonds, forming R²₂(8) rings. The overall conformation of the pyrrolizidine nucleus is folded about the bridging bond.

Methyl 11,2,3,3a-5a-hydr­oxy-1-methyl-10-oxo-4-phenyl 10H-indeno[1,2-b]furo[3,4-b]pyrrole-3a-carboxyl­ate

In the title compound, C₂₂H₂₁NO₅, the pyrrolidine ring and the five-membered ring in the indene group have envelope conformations, while the furan ring adopts a twist conformation. Weak inter­molecular C—H...O inter­actions link the mol­ecules into centrosymmetric dimers. The crystal packing is further stabilized by van der Waals forces.

1′-Methyl-4′,5-diphenyl-5,6,7,8,9,10-hexa­hydro-1,3-cyclo­hepta­pyrimidino[2,3-b]thia­zole-2-spiro-3′-pyrrolidine-2′-spiro-3′′-1H-indole-2′′,3(2H,3′′H)-dione

The pyrrolidine ring of the title compound, C₃₄H₃₂N₄O₂S, adopts an envelope conformation. The packing is stabilized by inter­molecular C—H...O and N—H...N inter­actions.

4′-(4-Bromo­benzo­yl)-1′-methyldispiro­[indole-3(2H),2′-pyrrolidine-3′,3′′(2′′H)-indole]-2,2′′-dione

In the title compound, C₂₆H₂₀BrN₃O₃, the central pyrrolidine ring adopts an envelope conformation. In the crystal structure, the mol­ecules exist as centrosymmetric N—H...O hydrogen-bonded dimers. The dimers are linked via C—H...O hydrogen bonds, forming a chain along the b axis.

4′-(4-Chloro­benzo­yl)-1′-methyldispiro­[indole-3(2H),2′-pyrrolidine-3′,3′′(2′′H)-indole]-2,2′′-dione

In the title compound, C₂₆H₂₀ClN₃O₃, the central pyrrolidine ring adopts an envelope conformation. In the crystal structure, the mol­ecules exist as centrosymmetric N—H...O hydrogen-bonded dimers. The dimers are linked via C—H...O hydrogen bonds, forming a chain along the b axis.

4′-(4-Methoxy­benzo­yl)-1′-methyldispiro­[indole-3(2H),2′-pyrrolidine-3′,3′′(2′′H)-indole]-2,2′′-dione

In the title compound, C₂₇H₂₃N₃O₄, the pyrrolidine ring adopts a half-chair conformation. Inversion-related mol­ecules are linked via N—H...O hydrogen bonds into a zigzag chain. In addition, inter­molecular C—H...O and C—H...π hydrogen bonds are observed.