organic compounds
The structure determination of the title compound, dimethyl (±)-3-methyl-2-oxo-6-phenyl-3,4,5,6-tetrahydro-2H-pyran-3,5- dicarboxylate, C16H18O6, unequivocally establishes its relative stereochemistry. The results provide strong support for the proposal that enolates derived from cis-5,6-disubstituted tetrahydro-2H-pyran-2-ones react very selectively with electrophiles trans to the C(5) and C(6) substituents.
Supporting information
Crystallographic Information File (CIF) | |
Structure factor file (CIF format) |
CCDC reference: 127148