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Domperidone maleate or 4-[5-chloro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl]-1-[(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]piperidinium maleate, an antiemetic drug, crystallizes as a 2.5-hydrate. The hydrogen-bonding interactions between the drug molecule, the maleate group and the water molecules stabilize the molecules in the lattice. Further stability comes from stacking interactions among the benzimidazole rings.

Supporting information

cif

Crystallographic Information File (CIF)
Contains datablocks global, qa0146

hkl

Structure factor file (CIF format)
Supplementary material

CCDC reference: 135862

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