cif-access (organic compounds)
Domperidone maleate or 4-[5-chloro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl]-1-[(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]piperidinium maleate, an antiemetic drug, crystallizes as a 2.5-hydrate. The hydrogen-bonding interactions between the drug molecule, the maleate group and the water molecules stabilize the molecules in the lattice. Further stability comes from stacking interactions among the benzimidazole rings.
Supporting information
Crystallographic Information File (CIF) | |
Structure factor file (CIF format) |
CCDC reference: 135862