Supporting information
Crystallographic Information File (CIF) https://doi.org/10.1107/S1600536807055638/is2230sup1.cif | |
Structure factor file (CIF format) https://doi.org/10.1107/S1600536807055638/is2230Isup2.hkl |
CCDC reference: 672858
The title compound was synthesized according to the procedure of Huang et al. (2006) in 85% isolated yield. Crystals of (I) suitable for X-ray data collection were obtained by slow evaporation of a DMF and MeOH solution in a ratio of 4:1 at 293 K.
One of the fluorophenyl groups was found to be disordered over two orientations. The occupancies refined to 0.751 (5) and 0.249 (5). The N-bound H atom was located in a difference map and the positional parameters were refined, with Uiso(H) = 1.2Ueq(N). The refined N—H distance is 0.85 (4) Å. Other H atoms were positioned geometrically (C—H = 0.93–0.98 Å) and refined using a riding model, with Uiso(H) = 1.2Ueq(C) or 1.5Ueq(methyl C).
Data collection: SMART (Bruker, 2001); cell refinement: SAINT (Bruker, 2001); data reduction: SAINT (Bruker, 2001); program(s) used to solve structure: SHELXS97 (Sheldrick, 1997); program(s) used to refine structure: SHELXL97 (Sheldrick, 1997); molecular graphics: SHELXTL (Bruker, 2001); software used to prepare material for publication: SHELXTL (Bruker, 2001).
C26H17ClF5N3O5 | F(000) = 1184 |
Mr = 581.88 | Dx = 1.519 Mg m−3 |
Monoclinic, P21/n | Mo Kα radiation, λ = 0.71073 Å |
Hall symbol: -P 2yn | Cell parameters from 7373 reflections |
a = 16.2280 (13) Å | θ = 2.6–26.7° |
b = 6.7102 (6) Å | µ = 0.23 mm−1 |
c = 23.772 (2) Å | T = 299 K |
β = 100.588 (1)° | Block, colorless |
V = 2544.5 (4) Å3 | 0.30 × 0.20 × 0.20 mm |
Z = 4 |
Bruker SMART APEX CCD area detector diffractometer | 5563 independent reflections |
Radiation source: fine-focus sealed tube | 4336 reflections with I > 2σ(I) |
Graphite monochromator | Rint = 0.023 |
ϕ and ω scans | θmax = 27.0°, θmin = 1.7° |
Absorption correction: multi-scan (SADABS; Sheldrick,1997) | h = −20→20 |
Tmin = 0.934, Tmax = 0.955 | k = −8→8 |
22744 measured reflections | l = −30→30 |
Refinement on F2 | Primary atom site location: structure-invariant direct methods |
Least-squares matrix: full | Secondary atom site location: difference Fourier map |
R[F2 > 2σ(F2)] = 0.054 | Hydrogen site location: inferred from neighbouring sites |
wR(F2) = 0.163 | H atoms treated by a mixture of independent and constrained refinement |
S = 1.03 | w = 1/[σ2(Fo2) + (0.0929P)2 + 0.7196P] where P = (Fo2 + 2Fc2)/3 |
5563 reflections | (Δ/σ)max = 0.001 |
375 parameters | Δρmax = 0.47 e Å−3 |
0 restraints | Δρmin = −0.40 e Å−3 |
C26H17ClF5N3O5 | V = 2544.5 (4) Å3 |
Mr = 581.88 | Z = 4 |
Monoclinic, P21/n | Mo Kα radiation |
a = 16.2280 (13) Å | µ = 0.23 mm−1 |
b = 6.7102 (6) Å | T = 299 K |
c = 23.772 (2) Å | 0.30 × 0.20 × 0.20 mm |
β = 100.588 (1)° |
Bruker SMART APEX CCD area detector diffractometer | 5563 independent reflections |
Absorption correction: multi-scan (SADABS; Sheldrick,1997) | 4336 reflections with I > 2σ(I) |
Tmin = 0.934, Tmax = 0.955 | Rint = 0.023 |
22744 measured reflections |
R[F2 > 2σ(F2)] = 0.054 | 0 restraints |
wR(F2) = 0.163 | H atoms treated by a mixture of independent and constrained refinement |
S = 1.03 | Δρmax = 0.47 e Å−3 |
5563 reflections | Δρmin = −0.40 e Å−3 |
375 parameters |
Geometry. All e.s.d.'s (except the e.s.d. in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell e.s.d.'s are taken into account individually in the estimation of e.s.d.'s in distances, angles and torsion angles; correlations between e.s.d.'s in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell e.s.d.'s is used for estimating e.s.d.'s involving l.s. planes. |
Refinement. Refinement of F2 against ALL reflections. The weighted R-factor wR and goodness of fit S are based on F2, conventional R-factors R are based on F, with F set to zero for negative F2. The threshold expression of F2 > σ(F2) is used only for calculating R-factors(gt) etc. and is not relevant to the choice of reflections for refinement. R-factors based on F2 are statistically about twice as large as those based on F, and R- factors based on ALL data will be even larger. |
x | y | z | Uiso*/Ueq | Occ. (<1) | |
C1 | 0.88345 (19) | 0.9362 (5) | 0.64714 (12) | 0.0825 (8) | |
C2 | 0.88883 (14) | 0.8305 (3) | 0.70435 (9) | 0.0552 (5) | |
C3 | 0.93968 (15) | 0.9015 (3) | 0.74941 (9) | 0.0588 (5) | |
H3 | 0.9698 | 1.0172 | 0.7458 | 0.071* | |
C4 | 0.94969 (14) | 0.8034 (3) | 0.80437 (9) | 0.0506 (5) | |
C5 | 0.84156 (14) | 0.5638 (3) | 0.75695 (9) | 0.0534 (5) | |
C6 | 0.7834 (2) | 0.5816 (5) | 0.65599 (11) | 0.0881 (9) | |
H6A | 0.7297 | 0.6451 | 0.6529 | 0.132* | |
H6B | 0.7772 | 0.4408 | 0.6610 | 0.132* | |
H6C | 0.8053 | 0.6057 | 0.6218 | 0.132* | |
C7 | 0.90085 (12) | 0.5314 (3) | 0.85767 (8) | 0.0455 (4) | |
C8 | 0.87154 (12) | 0.6237 (3) | 0.90172 (8) | 0.0454 (4) | |
H8 | 0.8468 | 0.7489 | 0.8964 | 0.055* | |
C9 | 0.87921 (12) | 0.5283 (3) | 0.95440 (8) | 0.0440 (4) | |
C10 | 0.91616 (12) | 0.3399 (3) | 0.96041 (8) | 0.0454 (4) | |
C11 | 0.94398 (14) | 0.2474 (3) | 0.91578 (9) | 0.0524 (5) | |
H11 | 0.9674 | 0.1207 | 0.9205 | 0.063* | |
C12 | 0.93680 (14) | 0.3443 (3) | 0.86379 (9) | 0.0519 (5) | |
H12 | 0.9559 | 0.2843 | 0.8333 | 0.062* | |
C14 | 0.80870 (14) | 0.7796 (3) | 1.00481 (9) | 0.0538 (5) | |
C15 | 0.79113 (15) | 0.8288 (4) | 1.06480 (9) | 0.0568 (5) | |
H15 | 0.8123 | 0.9617 | 1.0770 | 0.068* | |
C16 | 0.65624 (14) | 0.9874 (3) | 1.05906 (8) | 0.0529 (5) | |
C17 | 0.57840 (15) | 0.9618 (4) | 1.07377 (10) | 0.0651 (6) | |
H17 | 0.5623 | 0.8388 | 1.0862 | 0.078* | |
C18 | 0.52584 (16) | 1.1224 (5) | 1.06957 (12) | 0.0747 (7) | |
H18 | 0.4729 | 1.1055 | 1.0786 | 0.090* | 0.249 (5) |
C19 | 0.5473 (2) | 1.3048 (5) | 1.05286 (12) | 0.0805 (8) | |
H19 | 0.5111 | 1.4128 | 1.0518 | 0.097* | |
C20 | 0.6237 (2) | 1.3247 (4) | 1.03773 (13) | 0.0836 (8) | |
H20 | 0.6391 | 1.4482 | 1.0252 | 0.100* | 0.751 (5) |
C21 | 0.67913 (18) | 1.1675 (4) | 1.04039 (12) | 0.0715 (7) | |
H21 | 0.7310 | 1.1842 | 1.0297 | 0.086* | |
C22 | 0.83759 (15) | 0.7165 (4) | 1.16139 (9) | 0.0615 (6) | |
C23 | 0.87687 (17) | 0.5641 (5) | 1.19444 (10) | 0.0733 (7) | |
H23 | 0.8940 | 0.4497 | 1.1777 | 0.088* | |
C24 | 0.8901 (2) | 0.5852 (5) | 1.25253 (11) | 0.0857 (9) | |
C25 | 0.8651 (2) | 0.7482 (5) | 1.27896 (12) | 0.0861 (9) | |
H25 | 0.8746 | 0.7573 | 1.3187 | 0.103* | |
C26 | 0.82576 (19) | 0.8982 (5) | 1.24552 (12) | 0.0824 (8) | |
H26 | 0.8086 | 1.0118 | 1.2626 | 0.099* | |
C27 | 0.81105 (19) | 0.8823 (5) | 1.18607 (11) | 0.0767 (8) | |
H27 | 0.7834 | 0.9838 | 1.1634 | 0.092* | |
Cl1 | 0.93109 (4) | 0.22525 (8) | 1.02710 (2) | 0.05918 (19) | |
F1 | 0.93072 (17) | 1.1027 (4) | 0.65464 (9) | 0.1384 (9) | |
F2 | 0.91365 (15) | 0.8294 (4) | 0.60997 (7) | 0.1204 (8) | |
F3 | 0.80970 (13) | 0.9976 (4) | 0.62507 (9) | 0.1256 (8) | |
F4 | 0.92954 (19) | 0.4374 (4) | 1.28489 (8) | 0.1533 (11) | |
F5 | 0.44825 (14) | 1.0954 (5) | 1.08063 (13) | 0.1160 (12) | 0.751 (5) |
F5' | 0.6391 (6) | 1.4752 (10) | 1.0068 (3) | 0.107 (3) | 0.249 (5) |
H3A | 0.871 (2) | 0.556 (6) | 1.0340 (17) | 0.129* | |
N1 | 0.89657 (11) | 0.6373 (2) | 0.80425 (6) | 0.0469 (4) | |
N2 | 0.84131 (12) | 0.6632 (3) | 0.70551 (7) | 0.0563 (5) | |
N3 | 0.85381 (12) | 0.6140 (3) | 1.00225 (7) | 0.0545 (5) | |
O1 | 0.99850 (12) | 0.8528 (3) | 0.84664 (7) | 0.0683 (5) | |
O2 | 0.79781 (12) | 0.4212 (3) | 0.76047 (7) | 0.0780 (5) | |
O3 | 0.78186 (14) | 0.8891 (3) | 0.96539 (7) | 0.0821 (6) | |
O4 | 0.70443 (11) | 0.8169 (2) | 1.06338 (8) | 0.0644 (4) | |
O5 | 0.82930 (12) | 0.6831 (3) | 1.10315 (6) | 0.0727 (5) |
U11 | U22 | U33 | U12 | U13 | U23 | |
C1 | 0.0791 (18) | 0.114 (2) | 0.0576 (15) | 0.0048 (17) | 0.0198 (14) | 0.0289 (15) |
C2 | 0.0572 (13) | 0.0653 (13) | 0.0473 (11) | 0.0154 (10) | 0.0206 (10) | 0.0139 (9) |
C3 | 0.0713 (14) | 0.0582 (12) | 0.0500 (12) | 0.0016 (11) | 0.0192 (11) | 0.0115 (9) |
C4 | 0.0623 (13) | 0.0472 (10) | 0.0445 (10) | 0.0022 (9) | 0.0158 (9) | 0.0032 (8) |
C5 | 0.0579 (12) | 0.0604 (12) | 0.0425 (10) | 0.0002 (10) | 0.0109 (9) | 0.0020 (9) |
C6 | 0.095 (2) | 0.111 (2) | 0.0495 (13) | −0.0142 (18) | −0.0110 (13) | −0.0026 (14) |
C7 | 0.0502 (11) | 0.0483 (10) | 0.0380 (9) | −0.0019 (8) | 0.0083 (8) | 0.0051 (8) |
C8 | 0.0486 (11) | 0.0462 (10) | 0.0416 (10) | 0.0048 (8) | 0.0087 (8) | 0.0058 (8) |
C9 | 0.0434 (10) | 0.0499 (10) | 0.0388 (9) | 0.0009 (8) | 0.0082 (8) | 0.0047 (8) |
C10 | 0.0461 (10) | 0.0482 (10) | 0.0404 (9) | −0.0019 (8) | 0.0037 (8) | 0.0115 (8) |
C11 | 0.0602 (13) | 0.0432 (10) | 0.0532 (11) | 0.0066 (9) | 0.0088 (10) | 0.0064 (8) |
C12 | 0.0624 (13) | 0.0499 (11) | 0.0448 (10) | 0.0037 (9) | 0.0135 (9) | 0.0000 (8) |
C14 | 0.0592 (13) | 0.0590 (12) | 0.0436 (10) | 0.0067 (10) | 0.0104 (9) | 0.0033 (9) |
C15 | 0.0629 (13) | 0.0612 (12) | 0.0482 (11) | 0.0120 (10) | 0.0156 (10) | 0.0051 (9) |
C16 | 0.0584 (12) | 0.0557 (12) | 0.0454 (10) | 0.0053 (10) | 0.0119 (9) | −0.0046 (9) |
C17 | 0.0677 (15) | 0.0713 (15) | 0.0595 (13) | −0.0063 (12) | 0.0201 (11) | −0.0160 (11) |
C18 | 0.0584 (15) | 0.101 (2) | 0.0655 (15) | 0.0096 (14) | 0.0146 (12) | −0.0249 (14) |
C19 | 0.086 (2) | 0.088 (2) | 0.0665 (16) | 0.0330 (16) | 0.0116 (14) | −0.0071 (14) |
C20 | 0.104 (2) | 0.0643 (16) | 0.0851 (19) | 0.0186 (15) | 0.0228 (17) | 0.0117 (14) |
C21 | 0.0702 (16) | 0.0648 (14) | 0.0845 (17) | 0.0095 (12) | 0.0273 (14) | 0.0109 (13) |
C22 | 0.0621 (14) | 0.0810 (15) | 0.0451 (11) | 0.0121 (12) | 0.0194 (10) | 0.0060 (10) |
C23 | 0.0777 (17) | 0.0929 (18) | 0.0534 (13) | 0.0225 (15) | 0.0226 (12) | 0.0106 (12) |
C24 | 0.0880 (19) | 0.117 (2) | 0.0524 (14) | 0.0277 (18) | 0.0141 (13) | 0.0201 (15) |
C25 | 0.086 (2) | 0.125 (3) | 0.0460 (13) | 0.0088 (18) | 0.0090 (13) | 0.0008 (15) |
C26 | 0.090 (2) | 0.102 (2) | 0.0570 (14) | 0.0049 (17) | 0.0183 (14) | −0.0113 (14) |
C27 | 0.093 (2) | 0.0870 (18) | 0.0519 (13) | 0.0207 (15) | 0.0182 (13) | 0.0032 (12) |
Cl1 | 0.0670 (4) | 0.0602 (3) | 0.0492 (3) | 0.0042 (2) | 0.0075 (2) | 0.0205 (2) |
F1 | 0.168 (2) | 0.155 (2) | 0.0876 (13) | −0.0499 (18) | 0.0122 (13) | 0.0612 (14) |
F2 | 0.1407 (18) | 0.177 (2) | 0.0551 (9) | 0.0265 (15) | 0.0492 (11) | 0.0164 (11) |
F3 | 0.0993 (13) | 0.177 (2) | 0.0969 (13) | 0.0403 (14) | 0.0087 (11) | 0.0773 (14) |
F4 | 0.210 (3) | 0.177 (2) | 0.0691 (11) | 0.096 (2) | 0.0160 (14) | 0.0350 (13) |
F5 | 0.0706 (16) | 0.134 (2) | 0.152 (3) | 0.0061 (14) | 0.0437 (16) | −0.0359 (19) |
F5' | 0.156 (8) | 0.066 (4) | 0.093 (5) | 0.022 (4) | 0.007 (5) | 0.001 (4) |
N1 | 0.0576 (10) | 0.0485 (9) | 0.0354 (8) | 0.0017 (7) | 0.0106 (7) | 0.0029 (6) |
N2 | 0.0582 (11) | 0.0739 (12) | 0.0360 (8) | 0.0076 (9) | 0.0061 (7) | 0.0006 (8) |
N3 | 0.0632 (11) | 0.0629 (11) | 0.0395 (9) | 0.0129 (9) | 0.0152 (8) | 0.0097 (7) |
O1 | 0.0873 (12) | 0.0661 (10) | 0.0489 (9) | −0.0207 (9) | 0.0056 (8) | −0.0010 (7) |
O2 | 0.0875 (12) | 0.0848 (12) | 0.0570 (10) | −0.0268 (11) | 0.0004 (9) | 0.0027 (8) |
O3 | 0.1186 (15) | 0.0829 (12) | 0.0449 (8) | 0.0448 (11) | 0.0155 (9) | 0.0115 (8) |
O4 | 0.0674 (10) | 0.0515 (8) | 0.0794 (11) | 0.0045 (7) | 0.0274 (8) | 0.0028 (8) |
O5 | 0.0974 (13) | 0.0815 (11) | 0.0427 (8) | 0.0353 (10) | 0.0218 (8) | 0.0094 (8) |
C1—F3 | 1.283 (3) | C14—C15 | 1.541 (3) |
C1—F2 | 1.302 (4) | C15—O5 | 1.401 (3) |
C1—F1 | 1.348 (4) | C15—O4 | 1.403 (3) |
C1—C2 | 1.522 (3) | C15—H15 | 0.9800 |
C2—C3 | 1.315 (3) | C16—C21 | 1.362 (3) |
C2—N2 | 1.365 (3) | C16—O4 | 1.379 (3) |
C3—C4 | 1.445 (3) | C16—C17 | 1.382 (3) |
C3—H3 | 0.9300 | C17—C18 | 1.366 (4) |
C4—O1 | 1.206 (3) | C17—H17 | 0.9300 |
C4—N1 | 1.408 (3) | C18—F5 | 1.345 (4) |
C5—O2 | 1.204 (3) | C18—C19 | 1.352 (4) |
C5—N1 | 1.391 (3) | C18—H18 | 0.9300 |
C5—N2 | 1.392 (3) | C19—C20 | 1.360 (4) |
C6—N2 | 1.471 (3) | C19—H19 | 0.9300 |
C6—H6A | 0.9600 | C20—F5' | 1.299 (8) |
C6—H6B | 0.9600 | C20—C21 | 1.380 (4) |
C6—H6C | 0.9600 | C20—H20 | 0.9300 |
C7—C8 | 1.375 (3) | C21—H21 | 0.9300 |
C7—C12 | 1.380 (3) | C22—C27 | 1.364 (4) |
C7—N1 | 1.446 (2) | C22—C23 | 1.373 (3) |
C8—C9 | 1.392 (2) | C22—O5 | 1.384 (3) |
C8—H8 | 0.9300 | C23—C24 | 1.366 (4) |
C9—C10 | 1.395 (3) | C23—H23 | 0.9300 |
C9—N3 | 1.402 (2) | C24—F4 | 1.343 (3) |
C10—C11 | 1.375 (3) | C24—C25 | 1.360 (4) |
C10—Cl1 | 1.7387 (18) | C25—C26 | 1.366 (4) |
C11—C12 | 1.382 (3) | C25—H25 | 0.9300 |
C11—H11 | 0.9300 | C26—C27 | 1.394 (4) |
C12—H12 | 0.9300 | C26—H26 | 0.9300 |
C14—O3 | 1.208 (3) | C27—H27 | 0.9300 |
C14—N3 | 1.338 (3) | N3—H3A | 0.85 (4) |
F3—C1—F2 | 109.8 (3) | C21—C16—O4 | 125.1 (2) |
F3—C1—F1 | 104.7 (3) | C21—C16—C17 | 120.6 (2) |
F2—C1—F1 | 105.7 (3) | O4—C16—C17 | 114.2 (2) |
F3—C1—C2 | 114.3 (2) | C18—C17—C16 | 118.1 (3) |
F2—C1—C2 | 112.5 (3) | C18—C17—H17 | 121.0 |
F1—C1—C2 | 109.3 (2) | C16—C17—H17 | 121.0 |
C3—C2—N2 | 123.61 (19) | F5—C18—C19 | 118.7 (3) |
C3—C2—C1 | 118.9 (2) | F5—C18—C17 | 118.3 (3) |
N2—C2—C1 | 117.5 (2) | C19—C18—C17 | 123.0 (3) |
C2—C3—C4 | 121.4 (2) | C19—C18—H18 | 118.5 |
C2—C3—H3 | 119.3 | C17—C18—H18 | 118.5 |
C4—C3—H3 | 119.3 | C18—C19—C20 | 117.6 (3) |
O1—C4—N1 | 121.80 (18) | C18—C19—H19 | 121.2 |
O1—C4—C3 | 125.2 (2) | C20—C19—H19 | 121.2 |
N1—C4—C3 | 113.04 (19) | F5'—C20—C19 | 120.4 (5) |
O2—C5—N1 | 121.66 (19) | F5'—C20—C21 | 115.4 (5) |
O2—C5—N2 | 122.4 (2) | C19—C20—C21 | 122.1 (3) |
N1—C5—N2 | 115.97 (19) | C19—C20—H20 | 119.0 |
N2—C6—H6A | 109.5 | C21—C20—H20 | 119.0 |
N2—C6—H6B | 109.5 | C16—C21—C20 | 118.6 (3) |
H6A—C6—H6B | 109.5 | C16—C21—H21 | 120.7 |
N2—C6—H6C | 109.5 | C20—C21—H21 | 120.7 |
H6A—C6—H6C | 109.5 | C27—C22—C23 | 120.8 (2) |
H6B—C6—H6C | 109.5 | C27—C22—O5 | 125.6 (2) |
C8—C7—C12 | 121.87 (17) | C23—C22—O5 | 113.7 (2) |
C8—C7—N1 | 118.68 (17) | C24—C23—C22 | 118.1 (3) |
C12—C7—N1 | 119.40 (17) | C24—C23—H23 | 120.9 |
C7—C8—C9 | 119.47 (18) | C22—C23—H23 | 120.9 |
C7—C8—H8 | 120.3 | F4—C24—C25 | 118.7 (3) |
C9—C8—H8 | 120.3 | F4—C24—C23 | 118.2 (3) |
C8—C9—C10 | 118.33 (17) | C25—C24—C23 | 123.1 (3) |
C8—C9—N3 | 123.38 (18) | C24—C25—C26 | 118.1 (3) |
C10—C9—N3 | 118.27 (16) | C24—C25—H25 | 120.9 |
C11—C10—C9 | 121.73 (17) | C26—C25—H25 | 120.9 |
C11—C10—Cl1 | 119.57 (15) | C25—C26—C27 | 120.6 (3) |
C9—C10—Cl1 | 118.64 (15) | C25—C26—H26 | 119.7 |
C10—C11—C12 | 119.46 (18) | C27—C26—H26 | 119.7 |
C10—C11—H11 | 120.3 | C22—C27—C26 | 119.3 (3) |
C12—C11—H11 | 120.3 | C22—C27—H27 | 120.3 |
C7—C12—C11 | 119.11 (19) | C26—C27—H27 | 120.3 |
C7—C12—H12 | 120.4 | C5—N1—C4 | 125.71 (17) |
C11—C12—H12 | 120.4 | C5—N1—C7 | 117.09 (17) |
O3—C14—N3 | 126.3 (2) | C4—N1—C7 | 117.18 (16) |
O3—C14—C15 | 119.10 (19) | C2—N2—C5 | 120.07 (18) |
N3—C14—C15 | 114.58 (18) | C2—N2—C6 | 124.8 (2) |
O5—C15—O4 | 107.31 (18) | C5—N2—C6 | 115.0 (2) |
O5—C15—C14 | 108.54 (17) | C14—N3—C9 | 128.49 (17) |
O4—C15—C14 | 108.71 (19) | C14—N3—H3A | 115 (3) |
O5—C15—H15 | 110.7 | C9—N3—H3A | 116 (3) |
O4—C15—H15 | 110.7 | C16—O4—C15 | 120.45 (18) |
C14—C15—H15 | 110.7 | C22—O5—C15 | 119.20 (18) |
F3—C1—C2—C3 | −121.5 (3) | C22—C23—C24—F4 | −179.1 (3) |
F2—C1—C2—C3 | 112.5 (3) | C22—C23—C24—C25 | 1.1 (5) |
F1—C1—C2—C3 | −4.6 (4) | F4—C24—C25—C26 | 179.4 (3) |
F3—C1—C2—N2 | 59.9 (4) | C23—C24—C25—C26 | −0.7 (5) |
F2—C1—C2—N2 | −66.1 (3) | C24—C25—C26—C27 | 0.7 (5) |
F1—C1—C2—N2 | 176.8 (2) | C23—C22—C27—C26 | 1.4 (4) |
N2—C2—C3—C4 | 0.8 (4) | O5—C22—C27—C26 | −178.2 (3) |
C1—C2—C3—C4 | −177.7 (2) | C25—C26—C27—C22 | −1.0 (5) |
C2—C3—C4—O1 | 175.5 (2) | O2—C5—N1—C4 | −179.6 (2) |
C2—C3—C4—N1 | −3.6 (3) | N2—C5—N1—C4 | 1.3 (3) |
C12—C7—C8—C9 | 1.0 (3) | O2—C5—N1—C7 | 1.8 (3) |
N1—C7—C8—C9 | −176.61 (18) | N2—C5—N1—C7 | −177.28 (17) |
C7—C8—C9—C10 | −0.5 (3) | O1—C4—N1—C5 | −176.6 (2) |
C7—C8—C9—N3 | 177.68 (19) | C3—C4—N1—C5 | 2.6 (3) |
C8—C9—C10—C11 | −0.6 (3) | O1—C4—N1—C7 | 2.0 (3) |
N3—C9—C10—C11 | −178.9 (2) | C3—C4—N1—C7 | −178.86 (17) |
C8—C9—C10—Cl1 | 176.62 (15) | C8—C7—N1—C5 | −112.3 (2) |
N3—C9—C10—Cl1 | −1.7 (3) | C12—C7—N1—C5 | 70.0 (3) |
C9—C10—C11—C12 | 1.3 (3) | C8—C7—N1—C4 | 69.0 (2) |
Cl1—C10—C11—C12 | −175.96 (17) | C12—C7—N1—C4 | −108.7 (2) |
C8—C7—C12—C11 | −0.4 (3) | C3—C2—N2—C5 | 3.5 (3) |
N1—C7—C12—C11 | 177.22 (19) | C1—C2—N2—C5 | −177.9 (2) |
C10—C11—C12—C7 | −0.7 (3) | C3—C2—N2—C6 | 179.4 (3) |
O3—C14—C15—O5 | −179.1 (2) | C1—C2—N2—C6 | −2.1 (3) |
N3—C14—C15—O5 | 0.8 (3) | O2—C5—N2—C2 | 176.6 (2) |
O3—C14—C15—O4 | 64.4 (3) | N1—C5—N2—C2 | −4.4 (3) |
N3—C14—C15—O4 | −115.6 (2) | O2—C5—N2—C6 | 0.3 (3) |
C21—C16—C17—C18 | −0.6 (4) | N1—C5—N2—C6 | 179.4 (2) |
O4—C16—C17—C18 | −178.7 (2) | O3—C14—N3—C9 | −0.9 (4) |
C16—C17—C18—F5 | 176.2 (3) | C15—C14—N3—C9 | 179.1 (2) |
C16—C17—C18—C19 | −1.4 (4) | C8—C9—N3—C14 | 10.5 (4) |
F5—C18—C19—C20 | −175.1 (3) | C10—C9—N3—C14 | −171.3 (2) |
C17—C18—C19—C20 | 2.5 (4) | C21—C16—O4—C15 | 19.0 (3) |
C18—C19—C20—F5' | 160.7 (5) | C17—C16—O4—C15 | −163.0 (2) |
C18—C19—C20—C21 | −1.6 (5) | O5—C15—O4—C16 | 142.56 (19) |
O4—C16—C21—C20 | 179.2 (2) | C14—C15—O4—C16 | −100.2 (2) |
C17—C16—C21—C20 | 1.4 (4) | C27—C22—O5—C15 | 0.3 (4) |
F5'—C20—C21—C16 | −163.5 (5) | C23—C22—O5—C15 | −179.3 (2) |
C19—C20—C21—C16 | −0.3 (5) | O4—C15—O5—C22 | −76.2 (3) |
C27—C22—C23—C24 | −1.4 (4) | C14—C15—O5—C22 | 166.5 (2) |
O5—C22—C23—C24 | 178.2 (3) |
D—H···A | D—H | H···A | D···A | D—H···A |
C8—H8···O3 | 0.93 | 2.31 | 2.896 (3) | 121 |
C6—H6C···F2 | 0.96 | 2.37 | 3.046 (4) | 127 |
N3—H3A···O5 | 0.85 (4) | 2.07 (4) | 2.545 (2) | 115 (3) |
N3—H3A···Cl1 | 0.85 (4) | 2.44 (4) | 2.9074 (19) | 115 (3) |
Experimental details
Crystal data | |
Chemical formula | C26H17ClF5N3O5 |
Mr | 581.88 |
Crystal system, space group | Monoclinic, P21/n |
Temperature (K) | 299 |
a, b, c (Å) | 16.2280 (13), 6.7102 (6), 23.772 (2) |
β (°) | 100.588 (1) |
V (Å3) | 2544.5 (4) |
Z | 4 |
Radiation type | Mo Kα |
µ (mm−1) | 0.23 |
Crystal size (mm) | 0.30 × 0.20 × 0.20 |
Data collection | |
Diffractometer | Bruker SMART APEX CCD area detector diffractometer |
Absorption correction | Multi-scan (SADABS; Sheldrick,1997) |
Tmin, Tmax | 0.934, 0.955 |
No. of measured, independent and observed [I > 2σ(I)] reflections | 22744, 5563, 4336 |
Rint | 0.023 |
(sin θ/λ)max (Å−1) | 0.639 |
Refinement | |
R[F2 > 2σ(F2)], wR(F2), S | 0.054, 0.163, 1.03 |
No. of reflections | 5563 |
No. of parameters | 375 |
H-atom treatment | H atoms treated by a mixture of independent and constrained refinement |
Δρmax, Δρmin (e Å−3) | 0.47, −0.40 |
Computer programs: SMART (Bruker, 2001), SAINT (Bruker, 2001), SHELXS97 (Sheldrick, 1997), SHELXL97 (Sheldrick, 1997), SHELXTL (Bruker, 2001).
D—H···A | D—H | H···A | D···A | D—H···A |
C8—H8···O3 | 0.93 | 2.31 | 2.896 (3) | 121 |
C6—H6C···F2 | 0.96 | 2.37 | 3.046 (4) | 127 |
N3—H3A···O5 | 0.85 (4) | 2.07 (4) | 2.545 (2) | 115 (3) |
N3—H3A···Cl1 | 0.85 (4) | 2.44 (4) | 2.9074 (19) | 115 (3) |
The title compound, (I), is a new class of amide compounds having potential biological activity. Preliminary bioassay showed that the title compound had good herbicidal activity (Huang et al., 2006).
The molecular structure of (I) is shown in Fig. 1. The torsion angle of C9—N3—C14—C15 is 179.1 (2)°. The molecules are connected by two intermolecular Cl···O nonbonded interactions (Bruno et al., 1997) to form a dimer. The distance between atom Cl1 and atom O1 at (2 - x, 1 - y, 2 - z) is 3.0542 (18) Å. The crystal packing is stabilized by van der Waals forces.