journal menuBuy article online - an online subscription or single-article purchase is required to access this article.
research papers
The straightforward solution of the crystal structure of cyclosporin (C62H111N11O12·H2O) by a modified Shake-and-Bake procedure, using experimental neutron diffraction data alone, shows that the positivity of the density function is not a necessary prerequisite for solving the phase problem. The initial applications suggest the intriguing possibility that positivity may actually be a hindrance.
Subscribe to Acta Crystallographica Section A: Foundations and Advances
