Buy article online - an online subscription or single-article purchase is required to access this article.
organic compounds
The crystal structure of the monohydrate form of spirapril hydrochloride, (8S-{7[R*(R*)],8R*})-7-(2-{[1-(ethoxycarbonyl)-3-phenylpropyl]amino}-1- oxopropyl)-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylic acid hydrochloride, C22H31N2O5S2+.Cl-.H2O, was determined. The spirapril molecules adopt a trans conformation along the amide bond. The incorporated water molecules form hydrogen bonds with the host molecules.