Mannose Phenylhydrazone, an Acyclic Monosaccharide Derivative

In determining whether mannose phenylhydrazone (C₁₂H₁₈N₂O₅) is cyclic or acyclic, chemical and spectroscopic methods have yielded contradictory results. X-ray crystallography has now shown that this compound occurs in acyclic form in the solid state. The conformation is closely similar to that assumed by mannose p-bromophenylhydrazone [Furberg & Solbakk (1969). Acta Chem. Scand. 23, 3248-3256], and the hydrogen-bonding arrangements found in the two structures are identical.

-1