Supporting information
Crystallographic Information File (CIF) https://doi.org/10.1107/S1600536807042134/bi2232sup1.cif | |
Structure factor file (CIF format) https://doi.org/10.1107/S1600536807042134/bi2232Isup2.hkl |
CCDC reference: 1259309
A mixture of benzylamine (5.00 mmol) and o-vanillin (5.00 mmol) in methanol (40 ml) was refluxed with stirring for one hour to give an orange precipitate which was filtered and washed with methanol to give the title compound in 86% yield. Elemental analysis calculated: C 74.69, H 6.22, N 5.81%; found: C 74.66, H 6.12, N 5.79%.
H atoms were positioned geometrically with O—H = 0.82 Å and C—H = 0.93 or 0.96 Å, then constrained to ride on their parent atoms with Uiso(H) = xUeq(C), where x = 1.5 for methyl H, and 1.2 for all other H atoms.
Schiff bases have been utilized as ligands for a long time due to their straightforward synthesis and versatility in metal complexes. They therefore play an important role in the development of coordination chemistry as well as inorganic biochemistry, catalysis, optical materials and so on (Garnovskii et al., 1993; Huang et al., 2002). Considerable attention has been focused on the syntheses and structures of copper(II) and nickel(II) complexes. The nickel complexes with multidentate Schiff-base ligands have aroused particular interest because this metal can exhibit several oxidation states and may provide the basis for models of active sites of biological systems. The main attention with optically active Schiff-base complexes is concentrated on their catalytic abilities in stereo-selective synthesis (Bhadbhade & Srinivas, 1993; Bunce et al., 1998). As part of our research aiming to understand the molecular properties of chiral Schiff-base complexes, we describe here the synthesis and crystal structure of the title Schiff-base ligand (Figure 1).
For related literature, see: Bhadbhade & Srinivas (1993); Bunce et al. (1998); Garnovskii et al. (1993); Huang et al. (2002).
Data collection: APEX2 (Bruker, 2004); cell refinement: SAINT-Plus (Bruker, 2004); data reduction: SAINT-Plus (Bruker, 2004); program(s) used to solve structure: SHELXS97 (Sheldrick, 1997); program(s) used to refine structure: SHELXL97 (Sheldrick, 1997); molecular graphics: SHELXTL (Bruker, 2001); software used to prepare material for publication: SHELXTL (Bruker, 2001).
Fig. 1. The molecular structure of the title compound showing 30% probability displacement ellipsoids for non-H atoms. |
C15H15NO2 | F(000) = 512 |
Mr = 241.28 | Dx = 1.309 Mg m−3 |
Monoclinic, P21/c | Mo Kα radiation, λ = 0.71073 Å |
Hall symbol: -P 2ybc | Cell parameters from 2958 reflections |
a = 8.9236 (2) Å | θ = 2.3–28.1° |
b = 5.7681 (1) Å | µ = 0.09 mm−1 |
c = 23.8006 (2) Å | T = 293 K |
β = 92.432 (2)° | Block, colourless |
V = 1223.97 (4) Å3 | 0.26 × 0.24 × 0.12 mm |
Z = 4 |
Bruker APEXII CCD diffractometer | 2958 independent reflections |
Radiation source: fine-focus sealed tube | 1876 reflections with I > 2σ(I) |
Graphite monochromator | Rint = 0.020 |
φ and ω scans | θmax = 28.1°, θmin = 2.3° |
Absorption correction: multi-scan (SADABS; Bruker, 2000) | h = −10→11 |
Tmin = 0.978, Tmax = 0.990 | k = −7→7 |
8962 measured reflections | l = −31→31 |
Refinement on F2 | Primary atom site location: structure-invariant direct methods |
Least-squares matrix: full | Secondary atom site location: difference Fourier map |
R[F2 > 2σ(F2)] = 0.058 | Hydrogen site location: inferred from neighbouring sites |
wR(F2) = 0.202 | H-atom parameters constrained |
S = 1.00 | w = 1/[σ2(Fo2) + (0.1284P)2 + 0.1359P] where P = (Fo2 + 2Fc2)/3 |
2958 reflections | (Δ/σ)max = 0.003 |
165 parameters | Δρmax = 0.45 e Å−3 |
0 restraints | Δρmin = −0.39 e Å−3 |
C15H15NO2 | V = 1223.97 (4) Å3 |
Mr = 241.28 | Z = 4 |
Monoclinic, P21/c | Mo Kα radiation |
a = 8.9236 (2) Å | µ = 0.09 mm−1 |
b = 5.7681 (1) Å | T = 293 K |
c = 23.8006 (2) Å | 0.26 × 0.24 × 0.12 mm |
β = 92.432 (2)° |
Bruker APEXII CCD diffractometer | 2958 independent reflections |
Absorption correction: multi-scan (SADABS; Bruker, 2000) | 1876 reflections with I > 2σ(I) |
Tmin = 0.978, Tmax = 0.990 | Rint = 0.020 |
8962 measured reflections |
R[F2 > 2σ(F2)] = 0.058 | 0 restraints |
wR(F2) = 0.202 | H-atom parameters constrained |
S = 1.00 | Δρmax = 0.45 e Å−3 |
2958 reflections | Δρmin = −0.39 e Å−3 |
165 parameters |
Geometry. All e.s.d.'s (except the e.s.d. in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell e.s.d.'s are taken into account individually in the estimation of e.s.d.'s in distances, angles and torsion angles; correlations between e.s.d.'s in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell e.s.d.'s is used for estimating e.s.d.'s involving l.s. planes. |
Refinement. Refinement of F2 against ALL reflections. The weighted R-factor wR and goodness of fit S are based on F2, conventional R-factors R are based on F, with F set to zero for negative F2. The threshold expression of F2 > σ(F2) is used only for calculating R-factors(gt) etc. and is not relevant to the choice of reflections for refinement. R-factors based on F2 are statistically about twice as large as those based on F, and R- factors based on ALL data will be even larger. |
x | y | z | Uiso*/Ueq | ||
C1 | 0.2240 (3) | 0.5473 (5) | −0.01082 (11) | 0.0597 (7) | |
C2 | 0.2308 (3) | 0.3654 (5) | −0.04596 (12) | 0.0640 (7) | |
H11 | 0.2868 | 0.2332 | −0.0373 | 0.077* | |
C3 | 0.1488 (4) | 0.3901 (8) | −0.09541 (16) | 0.0889 (11) | |
H18 | 0.1501 | 0.2699 | −0.1214 | 0.107* | |
C4 | 0.0667 (4) | 0.5786 (8) | −0.10837 (15) | 0.0832 (10) | |
H15 | 0.0116 | 0.5850 | −0.1424 | 0.100* | |
C5 | 0.0631 (4) | 0.7614 (7) | −0.07204 (15) | 0.0821 (10) | |
H17 | 0.0074 | 0.8934 | −0.0811 | 0.098* | |
C6 | 0.1428 (4) | 0.7460 (6) | −0.02230 (13) | 0.0705 (8) | |
H14 | 0.1425 | 0.8672 | 0.0035 | 0.085* | |
C7 | 0.3131 (4) | 0.5078 (7) | 0.04205 (13) | 0.0771 (9) | |
H12A | 0.2776 | 0.3682 | 0.0599 | 0.093* | |
H12B | 0.4172 | 0.4837 | 0.0334 | 0.093* | |
C8 | 0.4167 (3) | 0.8313 (7) | 0.09167 (11) | 0.0698 (9) | |
H7 | 0.5043 | 0.8025 | 0.0730 | 0.084* | |
C9 | 0.4159 (3) | 1.0214 (6) | 0.13121 (11) | 0.0627 (8) | |
C10 | 0.2909 (3) | 1.0611 (5) | 0.16243 (10) | 0.0561 (7) | |
C11 | 0.2914 (3) | 1.2476 (5) | 0.20011 (11) | 0.0597 (7) | |
C12 | 0.1536 (4) | 1.4678 (7) | 0.26392 (15) | 0.0782 (9) | |
H13A | 0.2306 | 1.4617 | 0.2933 | 0.117* | |
H13B | 0.0570 | 1.4676 | 0.2802 | 0.117* | |
H13C | 0.1648 | 1.6068 | 0.2423 | 0.117* | |
C13 | 0.4141 (3) | 1.3927 (6) | 0.20707 (13) | 0.0690 (8) | |
H9 | 0.4130 | 1.5144 | 0.2327 | 0.083* | |
C14 | 0.5364 (3) | 1.3557 (7) | 0.17609 (15) | 0.0773 (9) | |
H16 | 0.6190 | 1.4535 | 0.1801 | 0.093* | |
C15 | 0.5382 (3) | 1.1745 (7) | 0.13892 (13) | 0.0753 (10) | |
H8 | 0.6228 | 1.1517 | 0.1181 | 0.090* | |
N1 | 0.3035 (3) | 0.7008 (5) | 0.08094 (9) | 0.0697 (7) | |
O1 | 0.1661 (2) | 1.2709 (4) | 0.22824 (9) | 0.0730 (7) | |
O2 | 0.1710 (2) | 0.9237 (4) | 0.15680 (8) | 0.0670 (6) | |
H2 | 0.1852 | 0.8256 | 0.1327 | 0.101* |
U11 | U22 | U33 | U12 | U13 | U23 | |
C1 | 0.0579 (15) | 0.0649 (17) | 0.0569 (14) | 0.0073 (12) | 0.0109 (11) | 0.0053 (12) |
C2 | 0.0709 (17) | 0.0586 (16) | 0.0630 (15) | 0.0114 (13) | 0.0089 (13) | −0.0047 (13) |
C3 | 0.088 (2) | 0.101 (3) | 0.078 (2) | −0.012 (2) | 0.0095 (18) | −0.023 (2) |
C4 | 0.067 (2) | 0.116 (3) | 0.0658 (18) | −0.012 (2) | −0.0051 (14) | 0.0036 (19) |
C5 | 0.074 (2) | 0.093 (3) | 0.078 (2) | 0.0119 (17) | −0.0122 (16) | 0.0131 (18) |
C6 | 0.0740 (18) | 0.0723 (19) | 0.0648 (16) | 0.0136 (15) | −0.0014 (14) | 0.0005 (15) |
C7 | 0.082 (2) | 0.088 (2) | 0.0613 (17) | 0.0314 (18) | 0.0042 (14) | 0.0068 (16) |
C8 | 0.0531 (15) | 0.106 (2) | 0.0503 (13) | 0.0250 (16) | 0.0068 (11) | 0.0195 (15) |
C9 | 0.0455 (13) | 0.095 (2) | 0.0476 (13) | 0.0132 (13) | 0.0032 (10) | 0.0198 (13) |
C10 | 0.0406 (12) | 0.0800 (18) | 0.0477 (12) | 0.0038 (11) | 0.0003 (9) | 0.0160 (12) |
C11 | 0.0477 (13) | 0.0786 (19) | 0.0530 (13) | 0.0035 (12) | 0.0028 (10) | 0.0137 (13) |
C12 | 0.0698 (18) | 0.100 (3) | 0.0659 (17) | 0.0036 (17) | 0.0089 (14) | −0.0046 (17) |
C13 | 0.0538 (15) | 0.085 (2) | 0.0675 (16) | −0.0037 (14) | −0.0020 (12) | 0.0145 (15) |
C14 | 0.0515 (15) | 0.102 (3) | 0.0781 (19) | −0.0111 (16) | 0.0025 (13) | 0.0179 (19) |
C15 | 0.0411 (13) | 0.119 (3) | 0.0662 (17) | 0.0057 (15) | 0.0086 (11) | 0.0276 (19) |
N1 | 0.0616 (14) | 0.0969 (19) | 0.0508 (12) | 0.0196 (13) | 0.0033 (10) | 0.0071 (12) |
O1 | 0.0525 (11) | 0.0963 (17) | 0.0711 (12) | −0.0048 (10) | 0.0131 (9) | −0.0105 (11) |
O2 | 0.0489 (10) | 0.0910 (16) | 0.0617 (11) | −0.0020 (9) | 0.0083 (8) | −0.0016 (10) |
C1—C2 | 1.345 (4) | C8—H7 | 0.930 |
C1—C6 | 1.378 (4) | C9—C10 | 1.386 (4) |
C1—C7 | 1.477 (4) | C9—C15 | 1.409 (5) |
C2—C3 | 1.367 (5) | C10—O2 | 1.334 (3) |
C2—H11 | 0.930 | C10—C11 | 1.401 (4) |
C3—C4 | 1.340 (6) | C11—O1 | 1.334 (3) |
C3—H18 | 0.930 | C11—C13 | 1.383 (4) |
C4—C5 | 1.365 (5) | C12—O1 | 1.425 (4) |
C4—H15 | 0.930 | C12—H13A | 0.960 |
C5—C6 | 1.357 (5) | C12—H13B | 0.960 |
C5—H17 | 0.930 | C12—H13C | 0.960 |
C6—H14 | 0.930 | C13—C14 | 1.360 (4) |
C7—N1 | 1.453 (5) | C13—H9 | 0.930 |
C7—H12A | 0.970 | C14—C15 | 1.370 (5) |
C7—H12B | 0.970 | C14—H16 | 0.930 |
C8—N1 | 1.277 (4) | C15—H8 | 0.930 |
C8—C9 | 1.445 (5) | O2—H2 | 0.820 |
C2—C1—C6 | 124.3 (3) | C10—C9—C15 | 117.6 (3) |
C2—C1—C7 | 111.9 (3) | C10—C9—C8 | 120.0 (3) |
C6—C1—C7 | 123.8 (3) | C15—C9—C8 | 122.4 (3) |
C1—C2—C3 | 114.7 (3) | O2—C10—C9 | 120.6 (3) |
C1—C2—H11 | 122.7 | O2—C10—C11 | 120.1 (2) |
C3—C2—H11 | 122.7 | C9—C10—C11 | 119.3 (3) |
C4—C3—C2 | 123.4 (3) | O1—C11—C13 | 123.8 (3) |
C4—C3—H18 | 118.3 | O1—C11—C10 | 114.7 (2) |
C2—C3—H18 | 118.3 | C13—C11—C10 | 121.5 (2) |
C3—C4—C5 | 120.5 (3) | O1—C12—H13A | 109.5 |
C3—C4—H15 | 119.7 | O1—C12—H13B | 109.5 |
C5—C4—H15 | 119.7 | H13A—C12—H13B | 109.5 |
C6—C5—C4 | 118.5 (3) | O1—C12—H13C | 109.5 |
C6—C5—H17 | 120.8 | H13A—C12—H13C | 109.5 |
C4—C5—H17 | 120.8 | H13B—C12—H13C | 109.5 |
C5—C6—C1 | 118.6 (3) | C14—C13—C11 | 119.3 (3) |
C5—C6—H14 | 120.7 | C14—C13—H9 | 120.3 |
C1—C6—H14 | 120.7 | C11—C13—H9 | 120.3 |
N1—C7—C1 | 112.4 (3) | C13—C14—C15 | 120.1 (3) |
N1—C7—H12A | 109.1 | C13—C14—H16 | 120.0 |
C1—C7—H12A | 109.1 | C15—C14—H16 | 120.0 |
N1—C7—H12B | 109.1 | C14—C15—C9 | 122.2 (3) |
C1—C7—H12B | 109.1 | C14—C15—H8 | 118.9 |
H12A—C7—H12B | 107.9 | C9—C15—H8 | 118.9 |
N1—C8—C9 | 123.5 (3) | C8—N1—C7 | 120.8 (3) |
N1—C8—H7 | 118.2 | C11—O1—C12 | 117.9 (2) |
C9—C8—H7 | 118.2 | C10—O2—H2 | 109.5 |
Experimental details
Crystal data | |
Chemical formula | C15H15NO2 |
Mr | 241.28 |
Crystal system, space group | Monoclinic, P21/c |
Temperature (K) | 293 |
a, b, c (Å) | 8.9236 (2), 5.7681 (1), 23.8006 (2) |
β (°) | 92.432 (2) |
V (Å3) | 1223.97 (4) |
Z | 4 |
Radiation type | Mo Kα |
µ (mm−1) | 0.09 |
Crystal size (mm) | 0.26 × 0.24 × 0.12 |
Data collection | |
Diffractometer | Bruker APEXII CCD |
Absorption correction | Multi-scan (SADABS; Bruker, 2000) |
Tmin, Tmax | 0.978, 0.990 |
No. of measured, independent and observed [I > 2σ(I)] reflections | 8962, 2958, 1876 |
Rint | 0.020 |
(sin θ/λ)max (Å−1) | 0.662 |
Refinement | |
R[F2 > 2σ(F2)], wR(F2), S | 0.058, 0.202, 1.00 |
No. of reflections | 2958 |
No. of parameters | 165 |
H-atom treatment | H-atom parameters constrained |
Δρmax, Δρmin (e Å−3) | 0.45, −0.39 |
Computer programs: APEX2 (Bruker, 2004), SAINT-Plus (Bruker, 2004), SHELXS97 (Sheldrick, 1997), SHELXL97 (Sheldrick, 1997), SHELXTL (Bruker, 2001).
Schiff bases have been utilized as ligands for a long time due to their straightforward synthesis and versatility in metal complexes. They therefore play an important role in the development of coordination chemistry as well as inorganic biochemistry, catalysis, optical materials and so on (Garnovskii et al., 1993; Huang et al., 2002). Considerable attention has been focused on the syntheses and structures of copper(II) and nickel(II) complexes. The nickel complexes with multidentate Schiff-base ligands have aroused particular interest because this metal can exhibit several oxidation states and may provide the basis for models of active sites of biological systems. The main attention with optically active Schiff-base complexes is concentrated on their catalytic abilities in stereo-selective synthesis (Bhadbhade & Srinivas, 1993; Bunce et al., 1998). As part of our research aiming to understand the molecular properties of chiral Schiff-base complexes, we describe here the synthesis and crystal structure of the title Schiff-base ligand (Figure 1).