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Search query: multidomain protein
184 articles match your search "multidomain protein"Results 1 to 10, sorted by relevance:
research papers
Open access
The crystal structure of the N-terminal part of T. thermophilus DnaJ unexpectedly showed an ordered GF domain and guided the design of a construct enabling the first structure determination of a complete DnaJ cochaperone molecule. By combining the crystal structures with spin-labelling EPR and cross-linking in solution, a dynamic view of this flexible molecule was developed.
research papers
The X-ray structure of BbgIII, a multidomain β-galactosidase from B. bifidum, determined using an intact protein corresponding to a gene construct of eight domains is reported.
crystallization communications
The multidomain cytoplasmic portion of the histidine protein kinase from an essential two-component signal transduction system has been crystallized and X-ray data have been collected to 2.8 Å resolution.
BIOLOGY | MEDICINE
Open access
The dietary compound resveratrol is an inhibitor of death-associated protein kinase 1.
research papers
The design of a new protein fold by fusion of a heterodimer is described.
BIOLOGY | MEDICINE
Open access
The anti-apoptotic multidomain protein XIAP is shown to be a compact dimer in solution as determined by an integrative approach combining NMR, SAXS, EPR and molecular modelling.
computer programs
DADIMODO is a program for refining atomic models of multidomain proteins or complexes against small-angle X-ray scattering data. Interdomain distance and orientational restraints, such as those derived from NMR measurements, can be included in the optimization process.
research papers
Crystals of aclacinomycin oxidoreductase are pseudomerohedrally twinned and are most likely to contain six twin domains. The structure was determined by multiwavelength anomalous diffraction using data from selenomethionine-substituted crystals.
research communications
FYCO1 plays an important role in the kinesin-dependent microtubule plus-end-directed transport of autophagosomes. Here, the crystal structure of the RUN domain of FYCO1 has been determined.
BIOLOGY | MEDICINE
Open access
High-resolution crystal structures of the ADP-ribose phosphatase domain (ADRP; also known as the macrodomain) from SARS-CoV-2 with multiple ligands illustrate how the protein undergoes conformational changes to adapt to the ligand in the manner observed for homologues from other viruses.