A pixel temporal averaging method is developed to eliminate motion artifacts and random noises aiming at real-time and in vivo radiology of mouse cerebral microvessels.

In this article, move contrast X-ray imaging (MCXI) based on high-brightness synchrotron radiation is developed. Experiments with live rodents demonstrate the practicability of the MCXI method for sensitive and intact imaging of microvessels in vivo.

This review focuses on recent progress in synchrotron radiation methodology and its application in probing neurovascular networks, especially the pathological changes associated with vascular abnormalities in various model systems.

The synchrotron-radiation-based phase-contrast imaging method is a more effective tool than absorption-contrast imaging for systematic visualization of cerebral microvasculature, which holds considerable promise for wider application in life sciences, including 3D micro-imaging in experimental models of neurodevelopmental and vascular disorders.

Synchrotron-radiation-based microvascular hemodynamic analysis was established in this study. Tumor vasculature analysis using this method showed unique characteristics of tumor blood flow in vivo.

Whole-body mouse microangiography was performed using synchrotron X-ray imaging.

Synchrotron radiation is utilized to assess both pulmonary vessel density and endothelial function in a Dahl rat model of congestive heart failure with secondary pulmonary hypertension.