search results
results of search on CRYSTALLOGRAPHY JOURNALS ONLINE ![Subscribe to an rss feed of this search Subscribe to an rss feed of this search](//journals.iucr.org/logos/rss_24.png)
Search query: binding sites at intermolecular interfaces
75 articles match your search "binding sites at intermolecular interfaces"Results 1 to 10, sorted by relevance:
![m logo](https://journals.iucr.org/logos/jicons/m_36x36.png)
virusMED (Virus Metal binding sites, Epitopes and Drug binding sites) is a rich internet application based on a database of atomic interactions around hotspots in 7041 experimentally determined viral protein structures.
![d logo](https://journals.iucr.org/logos/jicons/d_36x36.png)
In eight of the nine crystal structures of M. smegmatis MutT1 reported here, an arrangement is observed in which domain 1 of one molecule and domain 2 of a neighbouring molecule (trans domain 2) are brought into close proximity, with ligand-binding sites at the interface between the two domains. This and other structural observations, along with biochemical results, lead to a plausible proposal for the mechanism of action of the enzyme.
![d logo](https://journals.iucr.org/logos/jicons/d_36x36.png)
The crystal structure of starch synthase I from barley was refined to 2.7 Å resolution. It includes a regulatory disulfide and a bound oligosaccharide. Activity assays were performed on several mutants.
![d logo](https://journals.iucr.org/logos/jicons/d_36x36.png)
This paper presents a survey of techniques that explore the surface properties of protein:protein interfaces so as to inform the prediction of probable sites of protein:protein interaction on newly determined protein structures.
![d logo](https://journals.iucr.org/logos/jicons/d_36x36.png)
The structure of the new class of controller proteins (exemplified by C.Csp231I) in complex with its 21 bp DNA-recognition sequence is presented, and the molecular basis of sequence recognition in this class of proteins is discussed. An unusual extended spacer between the dimer binding sites suggests a novel interaction between the two C-protein dimers.
![d logo](https://journals.iucr.org/logos/jicons/d_36x36.png)
The dimeric structure of Sfh3 (Sec14 family homologue 3 in yeast) is reported for the first time and differs from the Sec14 proteins reported to date, all of which are monomeric.
![d logo](https://journals.iucr.org/logos/jicons/d_36x36.png)
The crystal structure of the effector-binding domain of the transcriptional repressor AraR from B. subtilis in complex with the effector molecule (L-arabinose) was determined at 2.2 Å resolution. A detailed analysis of the crystal identified a dimer organization that is distinctive from that of other members of the GalR/LacI family.
![d logo](https://journals.iucr.org/logos/jicons/d_36x36.png)
Structures of orthorhombic crystals of lysozyme at pH 4.5 show that the binding of phosphate ions produces long-range conformational changes and that low humidity produces a displacement of the fifth α-helix towards the active-site cavity. The interaction of some anions must be considered when analysing experiments with lysozyme at acidic pH values.
![d logo](https://journals.iucr.org/logos/jicons/d_36x36.png)
The crystal structures of adenylylated and unadenylylated GlnK, a PII protein from Corynebacterium glutamicum, indicate that adenylylation of Tyr51 in the T-loop does not interfere with the PII-typical conformational changes that occur in the T-loop upon effector binding. Rather, T-loop adenylylation further expands the repertoire of mechanisms that enable PII function.
![d logo](https://journals.iucr.org/logos/jicons/d_36x36.png)
In the course of soaking experiments of lytic polysaccharide monooxygenase crystals with potential oligosaccharide ligands, local changes in crystal packing, various degrees of active-site disorder and binding of oligosaccharides at potential branching or surface binding sites were observed.