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Search query: amphipol
2 articles match your search "amphipol"Results 1 to 2, sorted by relevance:
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Using the unique ability of small-angle neutron scattering to resolve a hydrogen-rich surfactant from a deuterated membrane protein, the results of removing free surfactant from the equilibrium are revealed.
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Preferred orientation of macromolecules is one of the major issues that are commonly encountered in obtaining isotropic cryo-EM maps. Here, a comprehensive examination was performed of how macromolecule orientations respond to changes in physical factors, such as freezing temperature, and chemical factors, such as the addition of surfactants, for a standard set of macromolecules, which provides insights into their behaviour on grids and can be utilized to address the preferred orientation problem in a systemic manner for any given macromolecule.