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Search query: Wilson's disease
9 articles match your search "Wilson's disease"Results 1 to 9, sorted by relevance:
crystallization communications
The modified N-domain of the Wilson disease protein has been crystallized both in its native form and as a selenomethionine derivative. X-ray diffraction data were collected from the native crystal to 1.7 Å resolution, while the selenomethionine derivative diffracted to 2.7 Å resolution.
research communications
Methanobactins are post-translationally modified copper-binding peptides that have a number of potential environmental and biomedical applications. This report presents the crystal structure and preliminary biochemical characterization of the putative methanobactin biosynthesis protein MbnF.
research papers
A PbII coordination polymer was prepared under solvothermal synthetic conditions using the bifunctional ligand 4,4′-(1H,1′H-[2,2′-biimidazole]-1,1′-diyl)dibenzoic acid and Pb(NO3)2. A two-dimensional (2D) coordination network is formed. The central PbII ions adopt distorted octahedral geometries, which are bound by the bifunctional ligand. Furthermore, the 2D coordination layers are assembled into a 3D supramolecular network through hydrogen-bonding interactions. In addition, a fluorescence sensing experiment towards Cu2+ based on the polymeric PbII complex was carried out.
BIOLOGY | MEDICINE
The anti-apoptotic multidomain protein XIAP is shown to be a compact dimer in solution as determined by an integrative approach combining NMR, SAXS, EPR and molecular modelling.
research papers
A complete set of data is presented, acquired using the Flyscan method after injection of gold-cluster-enriched mesoporous silica nanospheres, used as potential theranostic vectors, into rats.
crystallization papers
Recombinant dipeptidyl peptidase IV from P. gingivalis has been crystallized. Data were collected to 2.7 Å from selenomethionine-derived crystals and structure solution by SAD or MAD is in progress.
crystallization papers
S-Formylglutathione hydrolase has been crystallized and several crystallographic data sets have been collected to a maximum resolution of 1.6 Å. The space group changes from monoclinic C2 to trigonal P3121 or P3221 when the crystal is pressurized in a xenon pressure chamber.
research papers
Progress by the SPINE consortium on the determination of structures of proteins of bacterial and viral pathogens is outlined, with particular reference to the impact of high-throughput technologies.
metal-organic compounds
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The title compound, [Mo2(C5H10NS2)2O4]·C4H8O, can be readily prepared in tetrahydrofuran (THF) by an oxidation reaction between the MoIV precursor [MoO(S2CNEt2)2] with [ReMeO3]. The compound is an axially symmetric MoV dimer (2 symmetry), in which the metal atoms exhibit a distorted square-pyramidal coordination environment. A THF molecule was found to be equally disordered over two symmetry-related sites (around a twofold rotation axis), trans-coordinated to the apical oxido group and weakly interacting with the MoV atoms [Mo—O = 2.6213 (19) Å]. In the crystal, some weak C—H
O interactions occur between the terminal oxido and neighbouring —CH3 groups of an adjacent [Mo(μ-O)O(S2CNEt2)]2 unit.
O interactions occur between the terminal oxido and neighbouring —CH3 groups of an adjacent [Mo(μ-O)O(S2CNEt2)]2 unit.
