Three new pharmaceutical salts of the anti­oxidant drug emoxypine (EMX) with pharmaceutically acceptable maleic (Mlt), malonic (Mln) and adipic (Adp) acids ([EMX+Mlt], [EMX+Mln] and [EMX+Adp], respectively) were synthesized and their crystal structures characterized using single-crystal X-ray diffraction, solid-state DFT and QTAIMC analysis. The thermochemical and solubility properties of the three EMX salts were studied, with the maximum solubility increase (38 times) being observed for [EMX+Mln].