The structures of four nanobodies raised against the periplasmic domain of PorM were solved, and their interaction with their target was analysed. Diffracting crystals of two PorM constructs in complex with their specific nanobodies were obtained.

Two nanobodies raised against the cytoplasmic domain of GldL were produced, their interaction with their target was characterized, and their crystal structures were solved.

To complement the limitation of whole-mount transmission electron microscopy (TEM) for assessing dense granule deficiency, scanning transmission X-ray microscopy (STXM) was used to identify calcium-rich dense granules in human platelets. Based on STXM images of human platelets, their calcium maps were extracted to identify dense granules correctly and distinguish them from other granules such as α-granules.