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Acta Cryst. (2009). D65, 872-874
https://doi.org/10.1107/S0907444909017855

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Cross-linking of protein crystals as an aid in the generation of binary protein-ligand crystal complexes, exemplified by the human PDE10a-papaverine structure

O. A. Andersen, D. L. Schönfeld, I. Toogood-Johnson, B. Felicetti, C. Albrecht, T. Fryatt, M. Whittaker, D. Hallett and J. Barker

The crystal structure of PDE10a in complex with papaverine was generated by ligand soaking of protein crystals that were cross-linked by glutaraldehyde.

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