Subunits of Flock House virus (FHV) (T = 3) and Nudaurelia capensis ω virus (T = 4) spontaneously assemble when their respective genes program a baculovirus expression system. Virus-like particles of FHV were crystallized and diffract X-rays to 3.3 Å resolution.

Capsid-binding drugs that inhibit the first stage in picornaviral uncoating were used to select drug-resistant mutants of peliovirus type 3. Such mutants focus attention on parts of the capsid liable to have important functions in viral uncoating.