A novel family of four 1-bromo-2,6-bis­{[(λ⁵-phosphanyl­idene)imino]­meth­yl}benzene ligands has been synthesized and each ligand has been com­plexed with nickel(II). The phosphinimine substituents incrementally change from all-phenyl to all-cyclo­hexyl across this family and these ligands represent a useful opportunity to investigate the impact of changing sterics on com­plex structure and reactivity.

An image-guidance procedure for the small-animal microbeam radiotherapy stage at the Australian Synchrotron is demonstrated. The procedure encompassess imaging and semi-automatic alignment of samples prior to the radiotherapy, with a spatial accuracy of about 100 µm, demonstrated using phantoms.

The X-ray structure of the anti-IL-23 antibody CNTO4088 reveals an unusual conformation of CDR L1 despite the fact that the residues in key positions fit the pattern of the canonical structure.