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Diaminopimelate decarboxylase catalyses the last step in lysine biosynthesis: the decarboxylation of meso-diaminopimelate to form the essential amino acid S-lysine. Here, the crystallization of the two putative diaminopimelate decarboxylase isoforms from Arabidopsis thaliana, DapDc1 and DapDc2, are reported; the crystals diffracted to beyond 2.00 and 2.27 Å resolution, respectively.