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4 citations found for Kolade, O.
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Tomatinase, a saponin-detoxifying enzyme belonging to family 3 of the glycosyl hydrolases from the fungal tomato pathogen S. lycopersici, has been purified from culture medium and crystallized. The crystals belong to space group P21212 are predicted to contain 46% solvent and diffract to at least 3.0 Å resolution.
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The successful synthesis, characterization and analysis of intermolecular interactions of arylsulfonamide Schiff bases have been achieved, alongside their evaluation for inhibitory effects on tankyrase poly(ADP-ribose) polymerase in the context of colon cancer, through in-silico testing.
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The synthesis and characterization, crystal structures and DNA docking studies of a tetracyclic isoquinolinobenzothiadiazine and its two precursors are reported.
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Three o-nitrosulfonamides and three N-cycloamino-o-sulfanilamides have been successfully synthesized and characterized, and the intermolecular interactions analysed, as well as being tested in silico for carbonic anhydrase II (4iwz) and IX (5fl4) inhibitory activities. The results obtained from crystal packing and DFT analysis suggest that the molecules are held together by forces such as hydrogen bonding and π–π interactions.