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structural communications

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Acta Cryst. (2010). F66, 1013-1018
https://doi.org/10.1107/S1744309110029374

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Metal-ion dependence of the active-site conformation of the translesion DNA polymerase Dpo4 from Sulfolobus solfataricus

A. Irimia, L. V. Loukachevitch, R. L. Eoff, F. P. Guengerich and M. Egli

Structures of binary and ternary Dpo4 DNA polymerase complexes crystallized in the presence of Mg²⁺ have been determined. Comparisons with the corresponding Ca²⁺-form structures revealed subtle changes in the active-site geometry.

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