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Acta Cryst. (2018). D74, 560-571
https://doi.org/10.1107/S2059798318006496

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Approaches to altering particle distributions in cryo-electron microscopy sample preparation

I. Drulyte, R. M. Johnson, E. L. Hesketh, D. L. Hurdiss, C. A. Scarff, S. A. Porav, N. A. Ranson, S. P. Muench and R. F. Thompson

This paper describes different approaches that cryo-EM users can take to improve the quality of their sample distribution and ice for high-resolution single-particle cryo-EM.

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