7′-(Naphthalen-1-yl)-5′′-[(naphthalen-2-yl)­methyl­idene]-1′,3′,5′,6′,7′,7a′-hexa­hydro­dispiro­[acenaphthene-1,5′-pyrrolo­[1,2-c]thia­zole-6′,3′′-piperidine]-2(1H),4′′-dione

In the title compound, C₄₃H₃₄N₂O₂S, the six-membered piperidine ring adopts a half-chair conformation. The five-membered thia­zole ring adopts a slightly twisted envelope conformation and the pyrrole ring adopts an envelope conformation; in each case, the C atom linking the rings is the flap atom. The mol­ecular structure features inter- and intra­molecular C—H...O inter­actions. Furthermore, the crystal packing is stabilized by four inter­molecular C—H...π inter­actions.

1-Methyl-1′-(4-methyl­phen­yl)-2′,3′,5′,6′,7′,7a'-hexa­hydro-1′H-dispiro­[piperidine-3,2′-pyrrolizine-3′,3′′-indoline]-4,2′′-dione

The title compound, C₂₆H₂₉N₃O₂, crystallizes with two mol­ecules in the asymmetric unit, having C—H...O inter­actions between them and resulting in a dimer characterized by an R₂²(11) motif. These dimers are linked into an ABABAB chain via N—H...O, N—H...N and C—H...O built edge-fused R₁²(5) and R₂²(7) motifs. This chain is linked to its inversion-related partner via N—H...O bonds with an R²₂(8) motif and leads to a double chain extending along the b axis characterized by an R₆⁶(36) motif across the inversion centres. The methyl group of the phenyl ring and the oxindole of mol­ecule A and B are involved in C—H...π inter­actions. One C atom of the pyrrolizine ring of mol­ecule A and its attached H atoms show positional disorder, the major and minor components being in the ratio 0.706 (7):0.294 (7).

5-(4-Fluoro­benzyl­idene)-4′-(4-fluoro­phen­yl)-1,1′-dimethyl­dispiro­[piperidine-3,3′-pyrrolidine-2′,3′′-indoline]-4,2′′-dione

The asymmetric unit of the title compound, C₃₀H₂₇F₂N₃O₂, contains two independent mol­ecules. The pyrrolidine five-membered ring assumes an envelope conformation (with the CH₂ atom at the flap) in one mol­ecule and a twisted conformation in the other one. In both independent mol­ecules, the 4-piperidinone rings adopt a similar twisted chair conformation. In the crystal, the two independent mol­ecules form an R₂²(8) dimer through a pair of N—H...O hydrogen bonds; the R₂²(8) dimers are connected via weak C—H...O hydrogen bonds, leading to a chain extending along the c axis.

5′′-(2,4-Dichloro­benzyl­idene)-1′-(2,4-dichloro­phen­yl)-1′′-methyl-1′,2′,3′,5′,6′,7′,8′,8a'-octa­hydro­dispiro­[acenaphthyl­ene-1,3′-indolizine-2′,3′′-piperidine]-2,4′′(1H)-dione

In the title compound, C₃₇H₃₀Cl₄N₂O₂, the pyridinone ring adopts a twisted half-chair conformation. In the octa­hydro­indolizine fused-ring system, the piperidine ring is in a chair conformation and the pyrrole ring is twisted about the C—N bond linking the five- and six-membered rings. The mol­ecular structure features an intra­molecular C—H...O inter­action and the crystal packing is stabilized by C—H...π inter­actions.

5′′-Benzyl­idene-1′′-methyl-1′-phenyl-1′,2′,3′,5′,6′,7′,8′,8a'-octa­hydro­dispiro[acenaphthyl­ene-1,3′-indolizine-2′,3′′-piperidine]-2,4′′(1H)-dione

In the title compound, C₃₇H₃₄N₂O₂, the pyridinone ring adopts a half-chair conformation. In the octa­hydro­indolizine fused-ring system, the piperidine ring is in a chair conformation and the pyrrole ring is twisted about the N—C(piperidine) bond. The mol­ecular structure features a weak intra­molecular C—H...O inter­action.

5′′-(4-Chloro­benzyl­idene)-1′-(4-chloro­phen­yl)-1′′-methyl-1′,2′,3′,5′,6′,7′,8′,8a'-octa­hydro­dispiro­[acenaphthyl­ene-1,3′-indolizine-2′,3′′-piperidine]-2,4′′(1H)-dione

In the title compound, C₃₇H₃₂Cl₂N₂O₂, the pyridinone ring adopts a twisted half-chair conformation. The fused pyrrolidine and piperidine rings of the octa­hydro­indolizine unit exhibit envelope (with the C atom bound to the C atom bearing the chloro­benzene ring being the flap atom) and chair conformations, respectively. The dihedral angle between the chloro­benzene rings is 84.03 (1)°. In the crystal, C—H...π inter­actions lead to supra­molecular chains along [101] that assemble in the ac plane. Connections along the b axis are of the type Cl...Cl [3.4065 (8) Å].