Diffraction structural biology - introductory overview

An introductory overview to the special issue papers on diffraction structural biology in this issue of the journal.

A new paradigm for macromolecular crystallography beamlines derived from high-pressure methodology and results

Macromolecular crystallography at high pressure (HPMX) is a mature technique. Shorter X-ray wavelengths increase data collection efficiency on cryocooled crystals. Extending applications and exploiting spin-off of HPMX will require dedicated synchrotron radiation beamlines based on a new paradigm.