(E)-2-(4-Benz­yloxy-2-hy­droxy­benzyl­idene)-N-methyl­hydrazinecarbo­thio­amide

The mol­ecule of the title compound, C₁₆H₁₇N₃O₂S, adopts an E conformation with respect to the azomethine C=N bond. The hydrazinecarbo­thio­amide fragment is close to planar, with a largest deviation from the least-squares plane of 0.079 (2) Å for the hydrazide N atom. This fragment forms a dihedral angle of 9.43 (9)° with the central benzene ring. The benzene rings are inclined to one another by 67.55 (12)°. The mol­ecular conformation is stabilized by an intra­molecular O—H...N hydrogen bond involving the azomethine N atom. In the crystal, mol­ecules are linked through weak N—H...S and N—H...O hydrogen bonds into double ribbons along [010]. The crystal packing also features C—H...π inter­actions.

16-Oxa­penta­cyclo­[6.6.5.0^1,18.0^2,7.0^9,14]nona­deca-2,4,6,9,11,13,18-heptaen-15-one

In the title compound, C₁₈H₁₂O₂, the benzene rings are inclined to one another by 66.79 (7)°. The five-membered ring is almost planar with a maximum deviation of 0.014 (1) Å. In the crystal, the mol­ecules are linked by pairs of weak C—H...O interactions into centrosymmetric dimers. These dimers are linked by C—H...π interactions, forming a three-dimensional structure.

N′-[(1E)-1-(2-Fluoro­phen­yl)ethyl­idene]pyridine-3-carbohydrazide

The title compound, C₁₄H₁₂FN₃O, adopts an E conformation with respect to the azomethine double bond whereas the N and methyl C atoms are in a Z conformation with respect to the same bond. The ketonic O and azomethine N atoms are cis to each other. The non-planar mol­ecule [the dihedral angle between the benzene rings is 7.44 (11)°] exists in an amido form with a C=O bond length of 1.221 (2) Å. In the crystal, a bifurcated N—H...(O,N) hydrogen bond is formed between the amide H atom and the keto O and imine N atoms of an adjacent mol­ecule, leading to the formation of chains propagating along the b-axis direction. Through a 180° rotation of the fluoro­phenyl ring, the F atom is disordered over two sites with an occupancy ratio of 0.632 (4):0.368 (4).

(±)-trans-6,6′-Dieth­oxy-2,2′-[cyclo­hexane-1,2-diylbis(nitrilo­methanylyl­idene)]diphenol monohydrate

In the title hydrate, C₂₄H₃₀N₂O₄·H₂O, the organic mol­ecule adopts an E conformation with respect to the azomethine double bonds. The cyclo­hexane ring is in a chair conformation. The dihedral angle between benzene rings is 79.6 (2)°. Two intra­molecular O—H...N hydrogen bonds are present. In the crystal, the components are linked by O–H...O hydrogen bonds and weak C—H...π inter­actions, generating a three-dimensional supramolecular architecture.

Bis{μ-N-[(E)-4-benz­yloxy-2-oxidobenzyl­idene]-4-nitro­benzene­carbo­hydrazidato}bis­[di­aqua­nickel(II)] di­methyl­formamide tetra­solvate

The molecule of the title complex, [Ni₂(C₂₁H₁₅N₃O₅)₂(H₂O)₄]·4C₃H₇NO, is located on an inversion centre. This results in a dimeric Ni^II complex, with the two Ni^II atoms bridged by phenolate O atoms. The tridentate ligand is chelated to each Ni^II atom via one N and two O atoms of the imino­late form of the hydrazide moiety, which has the same conformation as the free ligand. The coordination geometry around each Ni^II ion is slightly distorted octa­hedral. A supra­molecular three-dimensional architecture is created by dominant inter­molecular O—H...N, O—H...O and C—H...O hydrogen-bonding inter­actions. These are augmented by two C—H...π inter­actions and a π–π inter­action with a centroid–centroid distance of 3.681 (2) Å.

N′-[(E)-Furan-2-ylmethyl­idene]-4-hydroxy­benzohydrazide

The title compound, C₁₂H₁₀N₂O₃, exists in the E conformation. The five-membered ring and the phenyl rings form dihedral angles of 36.73 (10) and 12.22 (10)°, respectively, with the central C(=O)N₂C unit. The crystal packing is dominated by strong N—H...O and O—H...N hydrogen bonds. Together with weaker C—H...O inter­actions, these establish a three-dimensional supra­molecular network.

Dichlorido{(2E)-2-[phen­yl(pyridin-2-yl)methyl­idene]hydrazinecarbo­thio­amide}cadmium(II) methanol monosolvate

In the title compound, [CdCl₂(C₁₃H₁₂N₄S)]·CH₃OH, the coord­ination geometry of the Cd^II ion is slightly distorted square-pyramidal, as indicated by the τ index of 0.36 (8). The S atom, two N atoms from the pyridyl-azomethine moiety and one of the Cl atoms comprise the basal plane, while the other Cl atom occupies the apical position. The hydrazinecarbo­thio­amide moiety adopts an E conformation with respect to the azomethine bond. The solvate mol­ecule in the crystal lattice plays a major role in inter­connecting adjacent mol­ecules by means of O—H...Cl and N—H...O hydrogen-bonding inter­actions. A supra­molecular three-dimensional architecture is sustained in terms of further N—H...Cl and C—H...Cl hydrogen-bonding inter­actions.

[2-Benzyl-3-(naphthalen-1-yl)-2,3-di­hydro-1,2-oxazole-4,5-di­yl]bis­(phenyl­methanone)

In the title compound, C₃₄H₂₅NO₃, the five-membered heterocyclic ring adopts an envelope conformation with the N atom as the flap. The plane through the four basal atoms of this ring makes dihedral angles of 69.78 (13), 53.15 (12) and 86.42 (13)°, respectively, with the benzene rings of the benzyl group and the two phenyl­methanone groups at the 4 and 5 positions, and of 78.60 (11)° with the naphthalenyl system. In the crystal, the mol­ecules are linked through C—H...O and C—H...π contacts into layers parallel to (101).

Crystal structure of (4-chloro­phen­yl)[2-(10-hy­droxy­phenanthren-9-yl)phenanthro[9,10-b]furan-3-yl]methanone

Mol­ecules of the title compound are arranged in the solid state in a three-dimensional supra­molecular architecture via inter­molecular O—H...O and C—H...O hydrogen bonding and through C—H...π inter­actions.

N′-[(E)-(3-Fluoro­pyridin-2-yl)methyl­idene]pyridine-3-carbohydrazide dihydrate

The organic molecule in the title dihydrate, C₁₂H₉FN₄O·2H₂O, exists in the E conformation with respect to the azo­methane C=N double bond. The mol­ecule is approximately planar, with a maximum deviation of 0.117 (1) Å for the carbonyl O atom from the mean plane of the mol­ecule. Both pyridine rings are essentially coplanar with the central C(=O)N₂C unit [dihedral angles = 1.99 (7) and 5.71 (8)°], exhibiting a significant difference in dihedral angles from its benzohydrazide analogue. The crystal packing features N—H...O, O—H...N and O—H...O hydrogen-bond inter­actions, which lead to the formation of a chain along the c-axis direction through one of the water mol­ecules present, and these chains are stacked one over the other by means of π–π inter­actions [with centroid–centroid distances of 3.7099 (10) and 3.6322 (10) Å] between the aromatic rings in neighbouring anti­parallel mol­ecules, building a three-dimensional supra­molecular network.

N′-[(E)-1-(2-Fluoro­phen­yl)ethyl­idene]pyridine-4-carbohydrazide

The title compound, C₁₄H₁₂FN₃O, adopts an E conformation with respect to the azomethine bond. The pyridyl and fluoro­benzene rings make dihedral angles of 38.58 (6) and 41.61 (5)° respectively with the central C(=O)N₂CC unit, resulting in a non-planar mol­ecule. The inter­molecular inter­actions comprise two classical N—H...O and N—H...N hydrogen bonds and four non-classical C—H...O and C—H...F hydrogen bonds. These inter­actions are augmented by a weak π–π inter­action between the benzene and pyridyl rings of neighbouring mol­ecules, with a centroid–centroid distance of 3.9226 (10) Å. This leads to a three-dimensional supra­molecular assembly in the crystal system. The F atom is disordered over two sites in a 0.559 (3): 0.441 (3) ratio, through a 180° rotation of the fluoro­benzene ring.

(2E,7E)-2,7-Bis[(thio­phen-2-yl)methyl­idene]cyclo­hepta­none

The whole molecule of the title compound, C₁₇H₁₆OS₂, is generated by two-fold rotational symmetry. The carbonyl C and O atoms of the cycloheptanone ring lie on the twofold rotation axis which bisects the opposite –CH₂–CH₂– bond of the ring. The mol­ecule exists in an E,E conformation with respect to the C=C double bond. The cyclo­hepta­none ring exhibits a twisted chair conformation and its mean plane makes a dihedral angle of 50.12 (19)° with the planes of the thio­phene rings. The two S atoms are in an anti arrangement with respect the carbonyl O atom and the dihedral angle between the two thio­phene ring planes is 69.38 (7)°. In the molecule, there are two intramolecular C—H...S hydrogen bond, forming S(6) ring motifs. In the crystal, inversion dimers are generated via pairs of C—H...O hydrogen bonds. These dimers are inter­connected by another inter­action of the same kind with a neighbouring mol­ecule, forming a mol­ecular chain along the c-axis direction.

Crystal structure of 2-[(E)-4-benz­yloxy-2-hy­droxy­benzyl­idene]-N-cyclo­hexyl­hydrazinecarbo­thio­amide aceto­nitrile hemisolvate

The asymmetric unit of the title compound, C₂₁H₂₅N₃O₂S·0.5C₂H₃N, contains two independent mol­ecules with almost similar structural properties along with a solvent mol­ecule of aceto­nitrile. The compound exists in the E conformation with respect to the azomethine C=N double bond. The hydrazinecarbo­thio­amide moieties in both independent mol­ecules are almost planar [maximum deviations of 0.013 (2) and 0.007 (2) Å]. The mol­ecular conformation is stabilized in each case by an intra­molecular N—H...N hydrogen bond. In the crystal, pairs of N—H...S hydrogen bonds link each of the independent mol­ecules into inversion dimers. The dimers are inter­connected by means of three C—H...π inter­actions.