research papers
The crystal structure of human RSK1 C-terminal kinase domain (CTKD) is reported at 2.7 Å resolution. The structure indicates that the autoinhibition of the CTKD is caused by an α-helix occupying the substrate-binding groove.
research papers
The crystal structure of the extended-spectrum β-lactamase OXY-1-1 has been determined at 1.93 Å resolution. Structural features around the catalytic cavity help to broaden the substrate profile of the enzyme.