5-(3,5-Di­fluoro­phen­yl)-1-(4-fluoro­phen­yl)-3-tri­fluoro­methyl-1H-pyrazole

In the title compound, C₁₆H₈F₆N₂, the dihedral angle between the pyrazole and di­fluoro­benzene rings is 50.30 (13)°, while those between the pyrazole and fluoro­benzene rings and between the di­fluoro­benzene and fluoro­benzene rings are 38.56 (13) and 53.50 (11)°, respectively. Aromatic π–π stacking inter­actions between adjacent di­fluoro­benzene rings [centroid–centroid separation = 3.6082 (11) Å] link the mol­ecules into dimers parallel to [21-2].

N′-Benzyl­idene-2-chloro-N-(4-chloro­phen­yl)acetohydrazide

In the title compound, C₁₅H₁₂Cl₂N₂O, the atoms not making up the chloro­benzene ring are approximately coplanar (r.m.s. deviation = 0.073 Å). The dihedral angle between these 13 atoms and the chloro­benzene ring is 67.37 (10)°. The C=O and Csp²—Cl groups are almost eclipsed [Cl—C—C=O = −6.5 (3)°]. In the crystal, C(6) chains linked by C—H...O hydrogen bonds result in [100] chains.

(1Z)-1-(1-Benzo­furan-2-yl)ethanone oxime

The title compound, C₁₀H₉NO₂, is almost planar (r.m.s. deviation for the non-H atoms = 0.027 Å) and the conformation across the C=N bond is syn. Further, the O atom of the benzo­furan ring is syn to the CH₃ group in the side chain. In the crystal, mol­ecules are linked into C(3) chains propagating in [010] by O—H...N hydrogen bonds.

(4-Fluoro­phen­yl)(4-hy­droxy-3-methyl­phen­yl)methanone

In the title compound, C₁₄H₁₁FO₂, the two benzene rings are not coplanar, with a dihedral angle of 57.45 (12)° between their planes. In the crystal, mol­ecules are linked by an O—H...O hydrogen bond, forming a 2₁ helical chain along the b axis.

2-(6-Hy­droxy-1-benzo­furan-3-yl)acetamide

In the title compound, C₁₀H₉NO₃, the dihedral angle between the benzo­furan ring system (r.m.s. deviation for the non-H atoms = 0.009 Å) and the –C—C(O)—N– segment is 83.76 (1)°. In the crystal, mol­ecules are linked by N—H...O and O—H...O hydrogen bonds, generating (001) sheets, which feature C(4) and C(10) chains.

2-(3,4-Di­meth­oxy­phen­yl)-4-(thio­phen-2-yl)-2,3-di­hydro-1,5-benzo­thia­zepine

In the title compound, C₂₁H₁₉NO₂S₂, the seven-membered thia­zepine ring adopts a slightly distorted twist boat conformation. The dihedral angle between the benzene rings is 67.4 (2)°. The mean plane of the thio­phene ring is twisted by 59.3 (2) and 87.7 (2)° from the mean planes of the benezene rings. In the crystal, inversion dimers linked by pairs of C—H...O hydrogen bonds generate R₂²(20) loops.

1-Fluoro-4-[(E)-2-nitro­vin­yl]benzene

The title compound, C₈H₆FNO₂, is almost planar (r.m.s. deviation for the non-H atoms = 0.019 Å) and the conformation across the C=C bond is trans. The C and H atoms of the side chain are disordered over two sets of sites in a 0.56 (3):0.44 (3) ratio. In the crystal, mol­ecules are linked by C—H...O inter­actions, thus forming C(5) chains propagating in [001].

4-(4-Methyl­phen­yl)-2-(prop-2-yn-1-yl)phthalazin-1(2H)-one

In the title compound, C₁₈H₁₄N₂O, the dihedral angle between the methyl­phenyl ring and the phthalazone ring system (r.m.s. deviation = 0.034 Å) is 53.93 (9)°. In the crystal, mol­ecules are connected by C—H...O hydrogen bonds, forming chains along [101]. The chains are linked by π–π inter­actions [centroid–centroid distance 3.6990 (12) Å], forming layers parallel to (10-1).

(E)-N′-[4-(Di­methyl­amino)­benzyl­idene]-2-(4-methyl­phen­oxy)acetohydrazide

In the title compound, C₁₈H₂₁N₃O₂, the dihedral angle between the benzene rings is 68.85 (11)°. In the crystal, the mol­ecules are linked by C—H...O and N—H...O hydrogen bonds, as well as weak C—H...π contacts, forming a three-dimensional supra­molecular architecture.

Crystal structure of 1-[(2S*,4R*)-6-fluoro-2-methyl-1,2,3,4-tetra­hydro­quinolin-4-yl]pyrrolidin-2-one

In the title compound, the 1,2,3,4-tetra­hydro­pyridine ring of the quinoline moiety adopts a half-chair conformation while the pyrrolidine ring has an envelope conformation. In the crystal, mol­ecules are linked by N—H...O and C—H...O hydrogen bonds, forming sheets lying parallel to (10), which are linked via C—H...F hydrogen bonds and C—H...π inter­actions, forming a three-dimensional structure.

6,7-Dimeth­oxy-2,4-di­phenyl­quinoline

In the title structure of the title compound, C₂₃H₁₉NO₂, two conformationally similar mol­ecules (A and B) comprise the asymmetric unit. The dihedral angle between phenyl rings bridged by the quinoline moiety are 76.25 (8)° in mol­ecule A and 70.39 (9)° in mol­ecule B. In the crystal, the independent mol­ecules are connected by C—H...O hydrogen bonds and the resulting dimeric aggregates are linked by π–π [inter-centroid distance = 3.7370 (8) Å] and C—H...π inter­actions, forming a three-dimensional architecture.

N-(4-Methyl­phenyl­sulfon­yl)-3-nitro­benzamide

In the title compound, C₁₄H₁₂N₂O₅S, the dihedral angle between the aromatic rings is 86.29 (1)° and the conformation between the C=O bond of the amide group and the meta-NO₂ group is syn. The C—S—N—C torsion angle is −65.87 (19)° and the mol­ecule has an L-shaped conformation. In the crystal, the mol­ecules are connected into inversion dimers through pairs of N—H...O hydrogen bonds and C—H...O inter­actions forming R₂²(8) and R₂²(14) loops, respectively. The dimers are connected by further C—H...O inter­actions, thereby forming (100) sheets.

N-(4-Meth­oxy­benzo­yl)benzene­sulfon­amide

In the title compound, C₁₄H₁₃NO₄S, the dihedral angle between the aromatic rings is 69.81 (1)°; the dihedral angle between the planes defined by the S—N—C=O segment of the central chain and the sulfonyl benzene ring is 74.91 (1)°. In the crystal, the mol­ecules are linked by weak N—H...O hydrogen bonds into C(4) chains running along [100]. The mol­ecules in adjacent chains are linked by weak C—H...O inter­actions, generating R₂² (16) dimeric pairs. Weak C—H...π inter­actions connect the double chains into (001) sheets.

N-(4-Meth­oxy­benzo­yl)-2-methyl­benzene­sulfonamide

In the title compound, C₁₅H₁₅NO₄S, the dihedral angle between the aromatic rings is 80.81 (1)° and the dihedral angle between the planes defined by the S—N—C=O fragment and the sulfonyl benzene ring is 86.34 (1)°. In the extended structure, dimers related by a crystallographic twofold axis are connected by pairs of both N—H...O hydrogen bonds and C—H...O inter­actions, which generate R₂²(8) and R₂²(14) loops, respectively. A weak aromatic π–π stacking inter­action is also observed [centroid–centroid separation = 3.7305 (3) Å].

2-Chloro-N-(4-meth­oxy­benzo­yl)­benzene­sulfonamide

In the title compound, C₁₄H₁₂ClNO₄S, the dihedral angle between the aromatic rings is 82.07 (1)° and the dihedral angle between the planes defined by the S—N—C=O fragment and the sulfonyl benzene ring is 82.46 (3)°. In the crystal, the mol­ecules are linked into C(4) chains running along [001] by strong N—H...O hydrogen bonds. A C—H...O intera­ction reinforces the [001] chains: its graph-set symbol is C(7). The chains are cross-linked into (100) sheets by further C—H...O inter­actions as C(6) chains along [001]. The structure also features weak π–π stacking inter­actions [centroid–centroid distances = 3.577 (1) and 3.8016 (1) Å].

N-Ethyl-2,2-dimethyl-N-(3-methyl­phen­yl)propanamide

In the title compound, C₁₄H₂₁NO, the conformation across the N—C(O) bond is syn-periplanar, the C—N—C—C torsion being −5.9 (5)°. The atoms of the ethyl group attached to the N atom are disordered over two sets of sites with occupancy ratios of 0.65 (2):0.35 (2) (CH₂) and 0.689 (14):0.311 (14) (CH₃)are linked by very weak C—H...O inter­actions forming C(8) chains along [001]. C—H...π inter­actions link the mol­ecules along the c-axis direction.

4-(Thio­phen-2-yl)-2-[4-(tri­fluoro­meth­yl)phen­yl]-2,3-di­hydro-1,5-benzo­thia­zepine

In the title compound, C₂₀H₁₄F₃NS₂, the seven-membered thia­zepine ring adopts a slightly distorted twist–boat conformation. The mean plane of the five-membered thio­phene ring fused to the thia­zepine ring is twisted by 32.3 (3) and 55.6 (4)° from the benzene and phenyl rings, respectively. In the crystal, inversion dimers linked by pairs of weak C—H...N inter­actions are observed.

(4-Fluoro­phen­yl)(2-hy­droxy-5-methyl­phen­yl)methanone

In the title compound, C₁₄H₁₁FO₂, the dihedral angles beteen the central C₃O ketone residue and the fluoro- and hy­droxy-substituted benzene rings are 50.44 (9) and 12.63 (10)°, respectively. The planes of the benzene rings subtend a dihedral angle of 58.88 (9)° and an intra­molecular O—H...O hydrogen bond closes an S(6) ring. No directional inter­actions beyond van der Waals packing contacts were identified in the crystal structure.

Crystal structure of (R)-6′-bromo-3,3-dimethyl-3′,4′-di­hydro-2′H-spiro­[cyclo­hexane-1,3′-1,2,4-benzo­thia­diazine] 1′,1′-dioxide

In the title compound, the mean plane of the cyclo­hexane ring is almost normal to the benzene ring and to the mean plane of the 1,2,4-thia­diazinane ring. In the crystal, mol­ecules are linked by N—H...O hydrogen bonds, forming chains along [10], which are in turn linked via C—H...π inter­actions, forming sheets parallel to (010).

Crystal structure of ethyl (6-hy­droxy-1-benzo­furan-3-yl)acetate sesquihydrate

The crystal structure of ethyl (6-hy­droxy-1-benzo­furan-3-yl)acetate sesquihydrate exhibits a one-dimensional hydrogen-bond motif consisting of (12) rings joined at water mol­ecules located on a twofold rotation axis.

5-(4-Chloro­phen­oxy)-3-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde

In the title compound, C₁₇H₁₃ClN₂O₂, the phenyl and chloro­benzene rings are inclined to the central pyrazole ring at 40.84 (9) and 65.30 (9)°, respectively. In the crystal, pairs of C—H...π inter­actions link the mol­ecules into inversion dimers and C—H...O hydrogen bonds link these dimers into columns extended in [010]. The crystal packing exhibits short inter­molecular O...Cl contacts of 3.0913 (16) Å.

2-Nitro­benzyl methane­sulfonate

In the title compound, C₈H₉NO₅S, the dihedral angle between the benzene ring and the nitro group is 5.86 (15)° and the C—C—O—S group adopts an anti conformation [torsion angle = −168.44 (15)°]. In the crystal, mol­ecules are linked by C—H...O hydrogen bonds, generating a three-dimensional network.

Bis(2-bromo­benz­yl) ether

In the title compound, C₁₄H₁₂Br₂O, the dihedral angle between the aromatic rings is 2.7 (3)° and the Br atoms lie on the same side of the mol­ecule. No inter­molecular inter­actions occur in the crystal beyond van der Waals contacts.

Crystal structure of N-(3-hy­droxy­phenyl)succinimide

In the title compound, C₁₀H₉NO₃, the dihedral angle between the benzene and pyrrolidine rings is 53.9 (1)°. In the crystal, mol­ecules are linked through strong O—H...O hydrogen bonds into zigzag C(8) chains running along [010]. The chains are linked by C—H...π inter­actions forming sheets lying parallel to (100).

Crystal structure of (E)-N-phenyl-N′-[1-(thio­phen-2-yl)ethyl­idene]formo­hydrazide

In the title compound, C₁₃H₁₂N₂OS, the planes of the thio­phene and phenyl rings are nearly perpendicular to each other, making a dihedral angle of 86.42 (12)°. In the crystal, mol­ecules are linked by C—H...O hydrogen bonds, forming a helical chain along the b-axis direction.

Crystal structure of 1-ethyl­spiro­[imid­az­olidine-4,1′-indane]-2,5-dione

In the title compound, C₁₃H₁₄N₂O₂, the C₅ ring has an envelope conformation with the C atom adjacent to the quaternary C being the flap. The five atoms comprising the imidazolidine-2,4-dione ring are almost planar (r.m.s. deviation = 0.004 Å). The dihedral angle between the five-membered rings is 89.66 (10)°. In the crystal, inversion-related mol­ecules are connected via {...HNCO}₂ synthons. These are linked into a helical supra­molecular chain along [010] by C—H...O inter­actions.

Crystal structure of cis-1-(2-methyl-1,2,3,4-tetra­hydro­quinolin-4-yl)azepan-2-one

In the title compound, C₁₆H₂₂N₂O, the azepan-2-one ring adopts a chair conformation, while the 1,2,3,4-tetra­hydro­pyridine ring adopts a half-chair conformation. In the crystal, mol­ecules are linked by N—H...O hydrogen bonds, forming supra­molecular chains propagated along [10-1], with weak C—H...O inter­actions occurring between the chains.

Crystal structure of 1′-(2-methyl­prop­yl)-2,3-di­hydro­spiro­[1-benzo­thio­pyran-4,4′-imidazolidine]-2′,5′-dione

In the title compound, C₁₅H₁₈N₂O₂S, the 2,3-di­hydro-1-benzo­thio­pyran ring adopts a sofa conformation and the hydantoin ring is twisted with respect to the benzene ring at 78.73 (17)°. In the crystal, pairs of N—H...O hydrogen bonds link the mol­ecules into inversion dimers.