Acta Crystallographica Section B
Acta Crystallographica
Section B
STRUCTURAL SCIENCE, CRYSTAL ENGINEERING AND MATERIALS
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Acta Cryst.
(2014).
B
70
,
555-567
https://doi.org/10.1107/S2052520614005125
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Understanding the structure details when drying hydrate crystals of pharmaceuticals - interpretations from diffuse scattering and inter-modulation satellites of a partially dehydrated crystal
E. J. Chan
,
Q. Gao
and
M. Dabros
A structural model has been developed to interpret the non-Bragg diffraction features that occur during the dehydration of an active pharmaceutical ingredient (API) hydrate crystal.
Keywords:
active pharmaceutical ingredients
;
diffuse scattering
;
dehydration
;
disordered layer structure
;
inter-modulation satellites
.
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