Acta Crystallographica Section D
Acta Crystallographica
Section D
STRUCTURAL BIOLOGY
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Acta Cryst.
(2013).
D
69
,
1633-1644
https://doi.org/10.1107/S0907444913011402
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The crystal structure reveals the molecular mechanism of bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II (Rv1415) from
Mycobacterium tuberculosis
M. Singh
,
P. Kumar
,
S. Yadav
,
R. Gautam
,
N. Sharma
and
S. Karthikeyan
This study represents the first crystal structure of bi-functional ribB/ribA enzyme from
Mycobacterium tuberculosis
.
Keywords:
DHBPS
;
GCHII
;
ribA2
;
GTP
;
riboflavin biosynthesis
;
antimicrobial targets
;
FMN
;
FAD
.
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