Acta Crystallographica Section D
Acta Crystallographica
Section D STRUCTURAL BIOLOGY

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Acta Cryst. (2013). D69, 860-865
https://doi.org/10.1107/S0907444913002771

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Effects of cryoprotectants on the structure and thermostability of the human carbonic anhydrase II-acetazolamide complex

M. Aggarwal, C. D. Boone, B. Kondeti, C. Tu, D. N. Silverman and R. McKenna

Here, a case study of the effects of cryoprotectants on the kinetics of carbonic anhydrase II (CA II) and its inhibition by the clinically used inhibitor acetazolamide (AZM) is presented.

Keywords: carbonic anhydrase; acetazolamide; cryoprotectants; glycerol; sucrose.

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