The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery

A focused strategy has been directed towards the structural characterization of selected proteins from the bacterial pathogen P. aeruginosa. The objective is to exploit the resulting structural data, in combination with ligand-binding studies, and to assess the potential of these proteins for early-stage antimicrobial drug discovery.

Preliminary crystallographic analysis of RraB from Escherichia coli

The crystallization and preliminary X-ray diffraction analysis of the ribonuclease regulator RraB from E. coli are reported.