Structural basis for the influence of a single mutation K145N on the oligomerization and photoswitching rate of Dronpa

N. Nguyen Bich, B. Moeyaert, K. Van Hecke, P. Dedecker, H. Mizuno, J. Hofkens and L. Van Meervelt

The structure of the on-state of PDM1-4, a single mutant of Dronpa, is reported, demonstrating the importance of β-barrel flexibility on the photoswitching kinetics by means of oligomerization.

Keywords: green fluorescent proteins; Dronpa; photoswitching.

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