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The title compound, C40H47FN2O5, crystallizes with two independent but similar mol­ecules in the asymmetric unit. In the crystal, mol­ecules are linked into chains along [100] by inter­molecular N—H...O hydrogen bonds.

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In the title compound, C28H29FN3O3PS, the pyrimidine ring is oriented at a dihedral angle of 50.9 (2)° with respect to the floro­benzene ring, while the two phenyl rings bonding to the same P atom are twisted with respect to each other, making a dihedral angle of 62.2 (2)°. In the crystal, mol­ecules are linked by weak C—H...O and C—H...F hydrogen bonds into a three-dimensional supra­molecular architecture.
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