Preliminary crystallographic studies of a Schistosoma mansoni antigen (Sm21.7) dynein light-chain (DLC) domain

Sm21.7, an S. mansoni tegumental protein that reduces the worm burden in a murine immunization model, was cloned, expressed and purified. Its C-terminal domain was crystallized and a native crystal diffracted to 2.05 Å resolution. An NaI derivative used for SIRAS phasing diffracted to 1.95 Å resolution.