The structure of the caspase recruitment domain of BinCARD reveals that all three cysteines can be oxidized

The mitochondrial localization of BinCARD and the susceptibility to oxidation of all three of its cysteines suggest the possibility of a role in redox regulation.

The TLR signalling adaptor TRIF/TICAM-1 has an N-­terminal helical domain with structural similarity to IFIT proteins

The structural and functional characterization of the N-terminal domain of the Toll-like receptor signalling adaptor TRIF/TICAM-1 is presented. The 2.22 Å resolution crystal structure was determined by selenomethionine-based SAD phasing using a protein containing two additional introduced methionines.