Structural basis of L-phosphoserine binding to Bacillus alcalophilus phosphoserine aminotransferase

The structures of Bacillus alcalophilus phosphoserine aminotransferase in the presence or absence of L-phosphoserine were determined at 1.5 and 1.6 Å resolution, respectively. Structural comparison revealed local conformational changes and the formation of a tight phosphate-binding site upon L-phosphoserine binding.