structural communications
The crystal structure of the N-terminal domain of lactoferrin-binding protein B (LbpB) from N. meningitidis is reported. Docking of the structure with lactoferrin suggests roles for LbpB in both host iron acquisition and neutralization of the toxic effects of the lactoferricin peptide.
crystallization communications
VHH R303 binds the Listeria virulence factor InlB. Crystals of R303 were obtained following in situ proteolysis with trypsin. Trypsin removed the flexible tag region of the protein, creating a homogeneous protein preparation. The crystals diffracted to 1.3 Å resolution.