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In the title compound, C16H12Cl2O3, the benzene rings form a dihedral angle of 2.0 (3)°. Within the central O=C—CH2C(H)OH—C=O unit, the carbonyl groups are coplanar and lie to opposite sides [O—C...C—O = −170.1 (6)°]. In the crystal, inter­molecular O—H...O hydrogen bonds formed between the hydr­oxy groups lead to a supra­molecular chain along the c axis. In addition, the crystal packing features some very weak C—H...π inter­actions.

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The title compound, C19H20N4O4, is a cyclo­nucleoside with a C—N linkage. The furan­ose ring adopts a twist C3′-endo/C2′-exo (close to 3T2) conformation with a pseudorotational phase angle (P) of 8.1° and puckering amplitude (vm) of 30.6°. The orientation of the pyrimidine ring with respect to the sugar group is anti. One intra­molecular C—H...O hydrogen bond is observed. The packing features an N—H...O hydrogen bond.
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