High-pressure cryocooling for capillary sample cryoprotection and diffraction phasing at long wavelengths

It is shown that a high-pressure cryocooling method enables the phasing of macromolecular structures using either Xe or native S atoms. The method may even be used for crystals in capillaries.

Structure of human upstream binding factor HMG box 5 and site for binding of the cell-cycle regulatory factor TAF1

The 2.0 Å resolution crystal structure of hUBF HMG box5 has been solved using the single-wavelength anomalous-dispersion method, and the possible sites in hUBF HMG box5 which may interact with the first bromodomain in TAF1 were proposed.