(25R)-16β-Acet­oxy-3β-bromo-23′,26-ep­oxy-23′,25-dimethyl-5α-cholest-23,23′-en-6-one dichloro­methane monosolvate

The crystal structure of the title compound, C₃₁H₄₅BrO₅·CH₂Cl₂, prepared in six steps from diosgenin, confirmed that the configurations of the stereogenic centers, positions 20S and 25R, remain unchanged during the reaction. The six-membered A, B and C rings have chair conformations. The five-membered ring D has an envelope conformation (with the methyl-substituted C atom fused to ring C as the flap) and the six-membered dihydro­pyran ring E adopts a twist-boat conformation. In the crystal, mol­ecules are linked via C—H...O and C—H...Cl hydrogen bonds, the latter involving the dichloro­methane solvent mol­ecule, forming a three-dimensional supra­molecular network.