Three closely-related cyclo­hexa­nols (C₃₅H₂₇X₂N₃O₃; X = F, Cl or Br): similar mol­ecular structures but different crystal structures

Three highly substituted cyclo­hexa­nols were prepared in satisfactory yield and with good stereospecificity by reaction of 4-halogenobenzaldehydes with 2-acetyl­pyridine under mild conditions. The mol­ecular structures of the cyclo­hexa­nols are very similar, but the crystal structures, particularly the space groups and the supra­molecular assemblies, are all different.