Methyl (3aRS,3cRS,6cSR,7RS,8RS,8aSR)-2,5-bis­(4-chloro­phen­yl)-7,9-bis­(1,3-diphenyl-1H-pyrazol-4-yl)-1,3,4,6-tetra­oxododeca­hydro-1H-dipyrrolo­[3,4-a:3',4'-f]pyrrolizine-3b-carboxyl­ate dimethyl­formamide disolvate: a three-dimensional hydrogen-bonded framework

The racemic title dipyrrolo­pyrrolizine compound crystallizes from dimethyl­formamide as a disolvate, C₅₅H₃₉Cl₂N₇O₆·2C₃H₇NO. None of the four fused heterocyclic rings is planar; one adopts an envelope conformation, two others adopt half-chair conformations and the fourth adopts a conformation inter­mediate between an envelope and a half-chair. The arrangement of the ring fusions is such as to preclude the possibility of inter­nal mirror symmetry. The three independent mol­ecular components are weakly linked by C-H...O hydrogen bonds, and the dipyrrolo­pyrrolizine mol­ecules are linked by a combination of four C-H...O and one C-H...[pi](arene) hydrogen bond to form a three-dimensional framework, from which the dimethyl­formamide solvent mol­ecules are pendent. However, aromatic [pi]-[pi] stacking inter­actions are absent in the structure.

(Z)-5-[(5-Methyl-1H-imidazol-4-yl)methyl­idene]-2-sulfanyl­idene-1,3-thia­zolidin-4-one monohydrate: a three-dimensional hydrogen-bonded framework structure

The non-H atoms in the organic component of the title compound, C₈H₇N₃OS₂·H₂O, are almost coplanar, as the dihedral angle between the two ring planes is only 1.8 (2)°; there is a wide C-C-C angle of 127.8 (3)° at the methine C atom linking the two rings. The mol­ecular components are linked into a three-dimensional framework structure by two-centre hydrogen bonds of N-H...O and O-H...N types, together with a three-centre O-H...(N,S) system. Comparisons are made with some (Z)-5-arylmethylidene-2-sulfanyl­idene-1,3-thia­zolidin-4-ones.