Ethyl 2-[({[4-amino-5-cyano-6-(methyl­sulfan­yl)pyridin-2-yl]carbamo­yl}meth­yl)sulfan­yl]acetate monohydrate

The title compound, C₁₃H₁₆N₄O₃S₂·H₂O, crystallizes in a `folded' conformation with the ester group lying over the carbamoyl moiety, with one solvent water mol­ecule. The mol­ecular conformation is stabilized by an intra­molecular C—H...O hydrogen bond, and an N—H...O hydrogen-bonding inter­action involving the lattice water mol­ecule. The packing involves N—H...N, N—H...O, O—H...N and O—H...O hydrogen bonds and consists of tilted layers running approximately parallel to the c axis, with the ester groups on the outer sides of the layers and with channels running parallel to (101).

3,4,6-Tri­amino-N-phenyl­thieno[2,3-b]pyridine-2-carboxamide

In the title compound, C₁₄H₁₃N₅OS, the dihedral angle between the fused ring system (r.m.s. deviation = 0.028 Å) and the phenyl ring is 48.24 (4)°. The mol­ecule features both an intra­molecular N—H...O and an N—H...N hydrogen bond. In the crystal, mol­ecules are linked by N—H...O and N—H...N hydrogen bonds, generating a three-dimensional network. A weak N—H...π inter­action is also observed.