organic compounds
Open access
In the title compound, C18H18F2N2O3S, the piperazine ring adopts a chair conformation. The dihedral angle between the sulfonyl-bound benzene ring and the best fit plane throught the six non-H atoms of the piperazine ring is 69.4 (2)°, while those between the fluorobenzene and sulfonyl rings and the fluorobenzene and piperazine rings are 30.97 (2) and 75.98 (2)°, respectively. In the crystal, molecules are connected to form a tetrameric unit through C—HO hydrogen bonds. The structure is further stabilized by weak intermolecular C—HF interactions, generating C(8) and C(7) chains running along [100].
organic compounds
Open access
The title compound, C10H16N4, crystalizes with two molecules (A and B) in the asymmetric unit in which the dihedral angles between the piperidine and pyrimidine rings are 47.5 (1) and 10.3 (1)°. The four C atoms of the pyrimidine ring in one of the molecules are disordered over two sets of sites with occupancy factors 0.508 (11):0.492 (11). In the crystal, the A molecules are linked to one another through N—HN hydrogen bonds, generating R22(8) ring patterns and forming inversion dimers. These dimers are further connected on either side to a B molecule through pairs of N—HN hydrogen bonds, resulting in a tetrameric unit.
organic compounds
Open access
In the crystal structure of the title compound, C19H21F3N2O2S, the piperazine ring adopts a chair conformation. The dihedral angles between the mean plane of the piperazine ring and the tosyl and trifluoromethylphenyl rings are 74.52 (3) and 68.30 (2)°, respectively. The sulfonamide N atom deviates from the plane defined by the three attached atoms by 0.327 (1) Å. The crystal structure is stabilized by weak C—Hπ interactions.