journal menu
organic compounds
Open 
access
access
In the title compound, C18H18F2N2O3S, the piperazine ring adopts a chair conformation. The dihedral angle between the sulfonyl-bound benzene ring and the best fit plane throught the six non-H atoms of the piperazine ring is 69.4 (2)°, while those between the fluorobenzene and sulfonyl rings and the fluorobenzene and piperazine rings are 30.97 (2) and 75.98 (2)°, respectively. In the crystal, molecules are connected to form a tetrameric unit through C—H
O hydrogen bonds. The structure is further stabilized by weak intermolecular C—HF interactions, generating C(8) and C(7) chains running along [100].
O hydrogen bonds. The structure is further stabilized by weak intermolecular C—HF interactions, generating C(8) and C(7) chains running along [100].organic compoundsOpen access
access
In the crystal structure of the title compound, C19H21F3N2O2S, the piperazine ring adopts a chair conformation. The dihedral angles between the mean plane of the piperazine ring and the tosyl and trifluoromethylphenyl rings are 74.52 (3) and 68.30 (2)°, respectively. The sulfonamide N atom deviates from the plane defined by the three attached atoms by 0.327 (1) Å. The crystal structure is stabilized by weak C—Hπ interactions.
π interactions.organic compoundsOpen access
access
In the title compound, C18H20Cl2N2O2S, the piperazine ring adopts a chair conformation. The dihedral angle between the sulfonyl-bound benzene ring and the best-fit plane through the six non-H atoms of the piperazine ring is 72.22 (12)°; those between the dichlorobenzene ring and the sulfonyl and piperazine rings are 2.44 (13) and 74.16 (2)°, respectively. In the crystal, molecules are connected through weak C—HO interactions into a hexameric unit generating a R66(60) motif in the ab plane. The molecules are also connected into C(4) chains through weak C—HN interactions. The solvent used to grow the crystal was a mixture of dichloromethane and methanol, but the resulting electron density was uninterpretable. The solvent contribution to the scattering was removed with the SQUEEZE routine in PLATON [Spek (2009). Acta Cryst. D65, 148–155]. The formula mass and unit-cell characteristics do not take into account the disordered solvent.
O interactions into a hexameric unit generating a R66(60) motif in the ab plane. The molecules are also connected into C(4) chains through weak C—HN interactions. The solvent used to grow the crystal was a mixture of dichloromethane and methanol, but the resulting electron density was uninterpretable. The solvent contribution to the scattering was removed with the SQUEEZE routine in PLATON [Spek (2009). Acta Cryst. D65, 148–155]. The formula mass and unit-cell characteristics do not take into account the disordered solvent. organic compoundsOpen access
access
In the title compound, C18H20F2N2O2S, the central piperazine ring adopts a chair conformation. The dihedral angle between the two benzene rings is 40.20°, whereas those between the piperazine ring (considering the best fit plane through all the non-H atoms) and the sulfonyl-bound benzene and difluorobenzene rings are 74.96 and 86.16°, respectively. In the crystal, molecules are stacked along the a axis through weak C—HO and C—HF interactions.
O and C—HF interactions.organic compoundsOpen access
access
In the title compound, C15H15NO4S, the dihedral angle between the benzene rings is 78.62 (16)°. In the crystal, adjacent molecules are linked along the c axis into C(4) chains through strong N—HO hydrogen bonds. Molecules are further connected through C—HO hydrogen bonds into a hexameric unit generating an R66(66) motif. Another C—HO interaction connects the molecules along the c axis, forming C(5) chains. A region of disordered electron density, most probably disordered methanol–water solvent molecules, was treated with the SQUEEZE routine in PLATON [Spek (2009). Acta Cryst. D65, 148–155]. The formula mass and unit-cell characteristics do not take into account this disordered solvent.
O hydrogen bonds. Molecules are further connected through C—HO hydrogen bonds into a hexameric unit generating an R66(66) motif. Another C—HO interaction connects the molecules along the c axis, forming C(5) chains. A region of disordered electron density, most probably disordered methanol–water solvent molecules, was treated with the SQUEEZE routine in PLATON [Spek (2009). Acta Cryst. D65, 148–155]. The formula mass and unit-cell characteristics do not take into account this disordered solvent.organic compoundsOpen access
access
The title compound, C14H12ClNO4S, crystallizes with two molecules in the asymmetric unit. The dihedral angles between the benzene rings are 89.68 (1) (molecule 1) and 82.9 (1)° (molecule 2). In each molecule, intramolecular N—HO hydrogen bonds between the amide H atom and the methoxy O atom generate S(6) loops. In the crystal, molecule 2 is linked into inversion dimers through pairs of C—HO interactions, forming an R22(8) ring motif. Molecules 1 and 2 are further linked along the b-axis direction through C—Hπ interactions. The crystal structure is further stabilized by several π–π stacking interactions [centroid–centroid separations = 3.7793 (1), 3.6697 (1) and 3.6958 (1) Å], thus generating a three-dimensional architecture.
O hydrogen bonds between the amide H atom and the methoxy O atom generate S(6) loops. In the crystal, molecule 2 is linked into inversion dimers through pairs of C—HO interactions, forming an R22(8) ring motif. Molecules 1 and 2 are further linked along the b-axis direction through C—Hπ interactions. The crystal structure is further stabilized by several π–π stacking interactions [centroid–centroid separations = 3.7793 (1), 3.6697 (1) and 3.6958 (1) Å], thus generating a three-dimensional architecture.
