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In the title compound, C18H18F2N2O3S, the piperazine ring adopts a chair conformation. The dihedral angle between the sulfonyl-bound benzene ring and the best fit plane throught the six non-H atoms of the piperazine ring is 69.4 (2)°, while those between the fluoro­benzene and sulfonyl rings and the fluoro­benzene and piperazine rings are 30.97 (2) and 75.98 (2)°, respectively. In the crystal, mol­ecules are connected to form a tetra­meric unit through C—H...O hydrogen bonds. The structure is further stabilized by weak inter­molecular C—H...F inter­actions, generating C(8) and C(7) chains running along [100].
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