organic compounds
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In the title compound, C15H12N2O·C3H7NO, carbamazepine molecules form the R22(8) N—HO hydrogen-bonded dimer arrangement observed in the crystal structures of each of the four known anhydrous polymorphs. The molecules of N,N-dimethylformamide are located between adjacent carbamazepine dimers and form an N—HO hydrogen bond to the anti-oriented NH group of the carboxamide moiety of carbamazepine.
organic compounds
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In the title compound, C15H12N2O·0.5C5H4O2, carbamazepine molecules retain the R22(8) N—HO hydrogen-bonded dimer arrangement observed in the crystal structures of each of the four known anhydrous polymorphs. The furfural molecule is located between adjacent carbamazepine dimers and is hydrogen bonded to only one of the anti-oriented NH groups available on the dimer.
organic compounds
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The solvate structure of 3,4-dichloro-1-nitrobenzene with aniline, 2C6H3Cl2NO2·C6H7N, is reported. Ribbons of 3,4-dichloronitrobenzene, formed by ClCl and N—OCl interactions, are linked together via N—HO hydrogen bonds with aniline into an undulating two-dimensional sheet.
organic compounds
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Hydrochlorothiazide forms a 1:1 solvate with aniline, C7H8ClN3O4S2·C6H7N. The crystal structure contains a hydrogen-bonding network comprising two N—HN and three N—HO contacts.
organic compounds
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Hydrochlorothiazide forms a 1:1 solvate with 1,4-dioxane, C7H8ClN3O4S2·C4H8O2 [systematic name: 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide–1,4-dioxane ()]. The asymmetric unit comprises one molecule of hydrochlorothiazide and halves of two solvent molecules arranged around inversion centres. The structure contains a hydrogen-bonding network comprising three N—HO and one N—HN hydrogen bonds.
organic compounds
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A polycrystalline sample of the title compound, C7H8ClN3O4S2·C3H6O2, was produced during an automated parallel crystallization search on hydrochlorothiazide (HCT). The crystal structure was solved by simulated annealing from laboratory X-ray powder diffraction data collected at room temperature to 1.75 Å resolution. Subsequent Rietveld refinement yielded an Rwp value of 0.0182 to 1.54 Å resolution. The compound crystallizes with one molecule of HCT and one of methyl acetate in the asymmetric unit and displays an extensive hydrogen-bonding network.
organic compounds
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The solvate structure of 3,4-dichloro-1-nitrobenzene with 1,4-dioxane, C6H3Cl2NO2·0.25C4H8N2, is reported. The asymmetric unit comprises two independent 3,4-dichloro-1-nitrobenzene molecules and half of a 1,4-dioxane molecule, the solvent molecule being disposed about a centre of inversion. Double chains of 3,4-dichloro-1-nitrobenzene are linked by ClCl interactions and 1,4-dioxane molecules via C—HO hydrogen bonds into a two-dimensional sheet.