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The title compound, 2,4-diamino-5-bromo-7-(2-deoxy-2-fluoro-[beta]-D-ara­bino­furanosyl)-7H-pyrrolo[2,3-d]pyrimidine, C11H13BrFN5O3, shows two conformations of the exocyclic C4'-C5' bond, with the torsion angle [gamma] (O5'-C5'-C4'-C3') being 170.1 (3)° for conformer 1 (occupancy 0.69) and 60.7 (7)° for conformer 2 (occupancy 0.31). The N-glycosylic bond exhibits an anti conformation, with [chi] = -114.8 (4)°. The sugar pucker is N-type (C3'-endo; 3T4), with P = 23.3 (4)° and [tau]m = 36.5 (2)°. The compound forms a three-dimensional network that is stabilized by several inter­molecular hydrogen bonds (N-H...O, O-H...N and N-H...Br).
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