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The history and development of high-pressure crystallography are briefly described and examples of structural transformations in compressed compounds are given. The review is focused on the diamond-anvil cell, celebrating its 50th anniversary this year, the principles of its operation and the impact it has had on high-pressure X-ray diffraction.

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Acta Cryst. (2008). A64, C436
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Acta Cryst. (2008). A64, C437
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Acta Cryst. (2008). A64, C612-C613
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