2,2':5,6-Di-O-iso­propyl­idene-2-C-hydro­xymethyl-D-talono-1,4-lactone

A second crystalline diacetonide, the title compound, C₁₃H₂₀O₇, has been isolated from the sequential treatment of D-tagatose with aqueous sodium cyanide, followed by acetone in the presence of acid. Structural ambiguities with regard to the size of both the lactone and ketal rings are resolved by the X-ray crystallographic analysis.

2-Acetamido-N-benz­yl-1,4-imino-1,2,4-tride­oxy-L-ribitol

The relative configuration of the stereocentres in a potential hexosaminidase inhibitor, C₁₄H₂₀N₂O₃, prepared from D-lyxonolactone, has been established using X-ray crystallographic techniques.

1-Amino-N,N-di­benzyl-1,6-di­deoxy-β-L-fructo­furan­ose

The title compound, C₂₀H₂₅NO₄, the product formed in the Amadori rearrangement of L-rhamnose with di­benzyl­amine, is shown by X-ray crystallographic analysis to be a rare example of an Amadori product crystallizing in a furan­ose form.

2-C-Methyl-D-allono-1,4-lactone

The relative stereochemistry at the quaternary C atom in the title compound, C₇H₁₂O₆, a 1,4-lactone formed from a protected D-ribonolactone, is firmly established by X-ray crystallographic analysis.

1-Amino-N,N-di­benzyl-1-deoxy-α-D-tagato­pyran­ose methanol solvate

The title tagatos­amine, C₂₀H₂₅NO₅.CH₄O, formed in the Amadori rearrangement of D-galactose with di­benzyl­amine, is shown to crystallize as the α-anomer, in contrast to the β-anomer formed in the Amadori reaction of D-glucose with di­benzyl­amine.

2-Acet­amido-N-benzyl-1,4-imino-1,2,4-tri­deoxy-L-arabinitol 0.33-hydrate

The solid-state conformation of the title compound, C₁₄H₂₀N₂O₃·0.33H₂O, a potent hexosaminidase inhibitor, prepared from D-lyxonolactone, has been established by X-ray crystallography. The asymmetric unit contains three mol­ecules, which have very similar conformations, together with a mol­ecule of water.